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Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGUS12122799, Compound JXW-572(CHEMBL4207168)
Affinity DataIC50: 170nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701271(US12122799, Compound Fosmidomycin)
Affinity DataIC50: 340nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGUS12122799, Compound FR-900098(CHEMBL1922604 | FR900098)
Affinity DataIC50: 360nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGUS12122799, Compound JXW-572(CHEMBL4207168)
Affinity DataIC50: 410nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50153713(3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | [3...)
Affinity DataIC50: 438nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701271(US12122799, Compound Fosmidomycin)
Affinity DataIC50: 670nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50: 843nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGUS12122799, Compound FR-900098(CHEMBL1922604 | FR900098)
Affinity DataIC50: 1.00E+3nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701274(US12122799, Compound ERJ-207)
Affinity DataIC50: 1.69E+3nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701274(US12122799, Compound ERJ-207)
Affinity DataIC50: 3.31E+3nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081647(CHEMBL3422252)
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081649(CHEMBL3422255)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701278(US12122799, Compound JXW-573)
Affinity DataIC50: 1.26E+4nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701278(US12122799, Compound JXW-573)
Affinity DataIC50: 1.52E+4nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081648(CHEMBL3422254)
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701275(US12122799, Compound RCB-185)
Affinity DataIC50: 1.00E+5nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM701275(US12122799, Compound RCB-185)
Affinity DataIC50: 1.00E+5nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Universiteit Gent

Curated by ChEMBL
LigandPNGBDBM50081650(CHEMBL3422256)
Affinity DataIC50: 2.73E+5nMAssay Description:Inhibition of recombinant Escherichia coli Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed