Compile Data Set for Download or QSAR
Report error Found 1807 with Last Name = 'congreve' and Initial = 'm'
TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280371(ethyl 4-[4- (1-methyl- 1H-imidazol- 2-yl)piperidin...)
Affinity DataEC50:  2.36E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280371(ethyl 4-[4- (1-methyl- 1H-imidazol- 2-yl)piperidin...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280372(ethyl 4-(4-{1- [(cyclohexyl- carbamoyl) methyl]- 1...)
Affinity DataEC50:  1.87E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280373(ethyl 4-[4-(1H- pyrrol-1- yl)piperidin- 1yl]azepan...)
Affinity DataEC50:  330nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280373(ethyl 4-[4-(1H- pyrrol-1- yl)piperidin- 1yl]azepan...)
Affinity DataEC50:  1.54E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280374(ethyl 4-[4-(1H- pyrazol-1- yl)piperidin- 1yl]azepa...)
Affinity DataEC50:  140nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280375(ethyl 4-{4-[5-(4- chlorophenyl)- 1H-pyrazol-1- yl]...)
Affinity DataEC50:  250nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280375(ethyl 4-{4-[5-(4- chlorophenyl)- 1H-pyrazol-1- yl]...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280376(ethyl 4-[4-(1H- pyrazol-3- yl)piperidin- 1yl]azepa...)
Affinity DataEC50:  190nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280377(ethyl 4-{4-[5-(1- methyl-1H- pyrazol-5-yl)- 1H-pyr...)
Affinity DataEC50:  260nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280377(ethyl 4-{4-[5-(1- methyl-1H- pyrazol-5-yl)- 1H-pyr...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280378(ethyl 4-{4-[4-(4- chlorophenyl)- 1H-pyrazol-1- yl]...)
Affinity DataEC50:  320nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280379(ethyl 4-[4-(1- methyl-1H- imidazol-2- yl)piperidin...)
Affinity DataEC50:  1.05E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280380(ethyl 4-[4- (1-ethyl- 1H-imidazol-2- yl)piperidin-...)
Affinity DataEC50:  1.74E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280381(ethyl 4-[4-(1- propyl-1H- imidazol-2- yl)piperidin...)
Affinity DataEC50:  960nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280382(ethyl 4-[4-(5- methyl-1H- pyrazol-1- yl)piperidin-...)
Affinity DataEC50:  520nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280382(ethyl 4-[4-(5- methyl-1H- pyrazol-1- yl)piperidin-...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280383(ethyl 4-[4- methoxy-4- (1-methyl-1H- imidazol-2- y...)
Affinity DataEC50:  2.88E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280384(ethyl 4-[4-(1- methyl-1H- pyrazol-5- yl)piperidin-...)
Affinity DataEC50:  750nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280385(ethyl 4-(4-(5- isopropyl-1,3,4- oxadiazol-2- yl)pi...)
Affinity DataEC50:  1.28E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280386(ethyl 4-[4- (3-methyl- 1H-pyrazol-1- yl)piperidin-...)
Affinity DataEC50:  400nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280386(ethyl 4-[4- (3-methyl- 1H-pyrazol-1- yl)piperidin-...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280387(ethyl 4-{4-[3- (thiophen-2-yl)- 1H-pyrazol-5- yl]p...)
Affinity DataEC50:  810nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280388(ethyl 4-{4-[4-(4- fluorophenyl)- 1H-pyrazol-1- yl]...)
Affinity DataEC50:  410nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280389(ethyl 4-(4-{1- [(cyclopropyl- carbamoyl) methyl]- ...)
Affinity DataEC50:  1.51E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280390(ethyl 4-[4-(5- cyclopropyl- 1H-pyrazol-1- yl)piper...)
Affinity DataEC50:  190nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280390(ethyl 4-[4-(5- cyclopropyl- 1H-pyrazol-1- yl)piper...)
Affinity DataEC50:  2.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280391(ethyl 4-{4-[5- (dimethyl- carbamoyl)- 1H-pyrazol-1...)
Affinity DataEC50:  2.68E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280392(ethyl 4-(4-{5- [1-(propan-2-yl)- 1H-pyrazol-4-yl]-...)
Affinity DataEC50:  200nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280392(ethyl 4-(4-{5- [1-(propan-2-yl)- 1H-pyrazol-4-yl]-...)
Affinity DataEC50:  680nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280393(ethyl 4-{4-[5- (methoxy- methyl)- 1H-pyrazol-1- yl...)
Affinity DataEC50:  750nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280394(ethyl 4-(4-{5- [(cyclopropyl- methyl) carbamoyl]- ...)
Affinity DataEC50:  1.37E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280395(ethyl 4-{4-[5- (dimethyl-1,3- thiazol-5-yl)- 1H-py...)
Affinity DataEC50:  270nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280396(ethyl 4-[4-(1,3- thiazol-2- yl)piperidin-1- yl]aze...)
Affinity DataEC50:  130nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280397(ethyl 4-[4-(5- cyano-1H- pyrazol-1- yl)piperidin-1...)
Affinity DataEC50:  320nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280398(ethyl 4-{4-[5- (acetamido- methyl)- 1H-pyrazol-1- ...)
Affinity DataEC50:  1.48E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280399(ethyl 4-{[3- (1H-pyrazol-1- yl)azetidin-1- yl]meth...)
Affinity DataEC50:  1.83E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280400(ethyl 4- [4-(pyridin- 4-yl)piperidin-1- yl]azepane...)
Affinity DataEC50:  1.66E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280401(ethyl 4- [4-(pyridin-4- yl)piperidin-1- yl]piperid...)
Affinity DataEC50:  2.26E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280402(ethyl 4-[4-(6- methoxypyridin- 2-yl)piperidin-1- y...)
Affinity DataEC50:  220nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280403(ethyl 4-[4-(6- methoxypyridin- 2-yl)piperidin-1- y...)
Affinity DataEC50:  180nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280404(ethyl 4-[4-(2- methoxypyridin- 3-yl)piperidin-1- y...)
Affinity DataEC50:  90nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280405(ethyl 4-[4-(2- methoxypyridin- 3-yl)piperidin- 1-y...)
Affinity DataEC50:  30nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280406(ethyl 4-[4-(2- methylpyrimidin- 4-yl)piperidin-1- ...)
Affinity DataEC50:  6.73E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280407(ethyl 4-[4-(4,6- dimethoxy- pyrimidin-2- yl)piperi...)
Affinity DataEC50:  3.34E+3nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280408(ethyl 4-[4-(3- methoxypyridin- 2-yl)piperidin-1- y...)
Affinity DataEC50:  30nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280408(ethyl 4-[4-(3- methoxypyridin- 2-yl)piperidin-1- y...)
Affinity DataEC50:  160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280409(ethyl 4-[4-(1- methyl-2-oxo-1,2- dihydropyridin-3-...)
Affinity DataEC50:  740nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280410(ethyl 4-[4-(3- methoxypyrazin- 2-yl)piperidin-1- y...)
Affinity DataEC50:  140nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280411(ethyl 4-[4-(2- methylpyridin-3- yl)piperidin-1- yl...)
Affinity DataEC50:  260nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
Go to US Patent

Displayed 1 to 50 (of 1807 total ) | Next | Last >>
Jump to: