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TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  237nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  229nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  182nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408214(CHEMBL4163852)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  687nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50160434(AM630 | (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-...)
Affinity DataEC50:  167nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataEC50:  270nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataEC50:  43nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataEC50:  1.35E+4nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556541(CHEMBL4756103)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataEC50:  586nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataEC50:  0.360nMAssay Description:Antagonist activity at human CB1R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  270nMAssay Description:Antagonist activity at human CB1R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataEC50:  120nMAssay Description:Partial agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556541(CHEMBL4756103)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataEC50:  17nMAssay Description:Inverse agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataEC50:  6.5nMAssay Description:Inverse agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  170nMAssay Description:Antagonist activity at human CB2R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  81nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  192nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  711nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  102nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  62nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  103nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cells assessed as potentiation of CP55940-stimulated inhibition of forskolin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50570252(CHEMBL4866198)
Affinity DataEC50:  15nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cells assessed as potentiation of CP55940-stimulated inhibition of forskolin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50570253(CHEMBL4467500)
Affinity DataEC50:  3.80nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cells assessed as potentiation of CP55940-stimulated inhibition of forskolin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50:  3.40nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cell membrane assessed as CP55940 EC50 for [35S]GTPgammaS binding at 1 nM me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
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