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LigandPNGBDBM430620(US10556914, Example 127)
Affinity DataEC50:  1.56E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060987(4'-Methyl-biphenyl-4-carboxylic acid | CHEMBL10751...)
Affinity DataKd:  1.50E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
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Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430522(US10556914, Example 2)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430574(US10556914, Example 66)
Affinity DataEC50:  2.79E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060996(4'-Trifluoromethyl-biphenyl-4-carboxylic acid | 4'...)
Affinity DataKd:  1.50E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
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Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430525(US10556914, Example 6)
Affinity DataEC50:  1.96E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430550(US10556914, Example 38)
Affinity DataEC50:  643nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430567(US10556914, Example 58)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430598(US10556914, Example 98)
Affinity DataEC50:  450nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060972(3',5'-Dichloro-biphenyl-4-carboxylic acid | CHEMBL...)
Affinity DataKd:  6.00E+4nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
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Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430575(US10556914, Example 67)
Affinity DataEC50:  2.13E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060994(4'-Carbamoyl-biphenyl-4-carboxylic acid | CHEMBL10...)
Affinity DataKd: >1.00E+7nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430616(US10556914, Example 120)
Affinity DataEC50:  6.82E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430523(US10556914, Example 3)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430534(US10556914, Example 16)
Affinity DataEC50:  222nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430588(US10556914, Example 82)
Affinity DataEC50:  23nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430541(US10556914, Example 24)
Affinity DataEC50:  1.85E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060970(2',4'-Dichloro-biphenyl-4-carboxylic acid | CHEMBL...)
Affinity DataKd:  3.50E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430587(US10556914, Example 79)
Affinity DataEC50:  511nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430604(US10556914, Example 106)
Affinity DataEC50:  847nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060975(4'-Cyano-biphenyl-4-carboxylic acid | CHEMBL323182)
Affinity DataKd: >1.00E+7nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060988((2E,4E)-5-(4-Phenoxy-phenyl)-penta-2,4-dienoic aci...)
Affinity DataKd:  3.50E+5nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM15029(3-[(2S)-2-amino-3-({5-[2-(pyridin-4-yl)phenyl]pyri...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM430532(US10556914, Example 13)
Affinity DataEC50:  3.54E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430572(US10556914, Example 64 | N-(4-methoxy-3-{3-methyl-...)
Affinity DataEC50:  644nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060982(2'-Methoxy-biphenyl-4-carboxylic acid | CHEMBL4327...)
Affinity DataKd:  1.70E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430570(US10556914, Example 61)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430562(US10556914, Example 53)
Affinity DataEC50:  620nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430592(US10556914, Example 87)
Affinity DataEC50:  1.03E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430596(US10556914, Example 96)
Affinity DataEC50:  2.59E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM15028(5-[(2S)-2-amino-3-phenylpropoxy]-N-(pyridin-3-ylme...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM430524(US10556914, Example 4)
Affinity DataEC50:  1.66E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430536(US10556914, Example 19)
Affinity DataEC50:  1.58E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430581(US10556914, Example 73)
Affinity DataEC50:  39nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430535(US10556914, Example 18)
Affinity DataEC50:  389nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM15027(5-[(2S)-2-amino-3-phenylpropoxy]-N-(pyridin-4-ylme...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060984(4'-Chloro-biphenyl-4-carboxylic acid | CHEMBL10578...)
Affinity DataKd:  1.60E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430538(US10556914, Example 21)
Affinity DataEC50:  229nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430605(US10556914, Example 107)
Affinity DataEC50:  1.47E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430553(US10556914, Example 41)
Affinity DataEC50:  4.67E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430539(US10556914, Example 22)
Affinity DataEC50:  2.69E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430566(US10556914, Example 57)
Affinity DataEC50:  3.33E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
Entry Details
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LigandPNGBDBM430602(US10556914, Example 103)
Affinity DataEC50:  439nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430612(US10556914, Example 116)
Affinity DataEC50:  855nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060969(4-(4-Phenoxy-phenyl)-butyric acid | CHEMBL321615)
Affinity DataKd:  1.90E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM430607(US10556914, Example 111)
Affinity DataEC50: >1.00E+4nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
Entry Details
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LigandPNGBDBM430613(US10556914, Example 117)
Affinity DataEC50:  43nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
Entry Details
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LigandPNGBDBM430555(US10556914, Example 45)
Affinity DataEC50:  376nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
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LigandPNGBDBM430614(US10556914, Example 118)
Affinity DataEC50:  2.93E+3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
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Date in BDB:
11/13/2020
Entry Details
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TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060999(3'-Trifluoromethyl-biphenyl-4-carboxylic acid | CH...)
Affinity DataKd:  3.20E+5nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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