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TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482250(CHEMBL1163166)
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV 3B reverse transcriptase using [3H]TTP as a tracer by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50050533(TNK-651 | 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL U...)
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601257(CHEMBL5178276)
Affinity DataIC50: 48nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601254(CHEMBL5190048)
Affinity DataIC50: 61nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601255(CHEMBL5172911)
Affinity DataIC50: 69nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601258(CHEMBL5198248)
Affinity DataIC50: 93nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482255(CHEMBL1164684)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV 3B reverse transcriptase using [3H]TTP as a tracer by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482252(CHEMBL1163165)
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV 3B reverse transcriptase using [3H]TTP as a tracer by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468858(CHEMBL1651642)
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 260nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601256(CHEMBL5193934)
Affinity DataIC50: 440nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483612(CHEMBL1761478)
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482251(CHEMBL1163681)
Affinity DataIC50: 710nMAssay Description:Inhibition of HIV 3B reverse transcriptase using [3H]TTP as a tracer by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483613(CHEMBL1761474)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483322(CHEMBL1651644)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601253(CHEMBL5172081)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483610(CHEMBL1761475)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468859(CHEMBL1651640)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483611(CHEMBL1761476)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482249(CHEMBL1163797)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483607(CHEMBL1761473)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482253(CHEMBL1165709)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482254(CHEMBL1163556)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483323(CHEMBL1651643)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601252(CHEMBL5171569)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483611(CHEMBL1761476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482252(CHEMBL1163165)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482246(CHEMBL1163770)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468860(CHEMBL1651645)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482250(CHEMBL1163166)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483609(CHEMBL1761471)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482251(CHEMBL1163681)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483607(CHEMBL1761473)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482255(CHEMBL1164684)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483606(CHEMBL1761472)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483606(CHEMBL1761472)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483609(CHEMBL1761471)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482245(CHEMBL1163802)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483613(CHEMBL1761474)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483608(CHEMBL1761477)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482247(CHEMBL1163769)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482248(CHEMBL1163766)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468814(CHEMBL1651646)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468813(CHEMBL1649606)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483321(CHEMBL1651641)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50482256(CHEMBL1164863)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV 3B integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483613(CHEMBL1761474)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483606(CHEMBL1761472)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483607(CHEMBL1761473)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50483610(CHEMBL1761475)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
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