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LigandPNGBDBM50032737(CHEMBL3354718)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061780(CHEMBL3394226)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061775(CHEMBL3394225)
Affinity DataKi:  6.90E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061587(CHEMBL3394051)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061594(CHEMBL3394041)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061595(CHEMBL3394042)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061583(CHEMBL3394047)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061593(CHEMBL3394040)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061582(CHEMBL3394039)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061584(CHEMBL3394048)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061581(CHEMBL3394058)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061580(CHEMBL3394057)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061592(CHEMBL3394056)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061591(CHEMBL3394055)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061590(CHEMBL3394054)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061589(CHEMBL3394053)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061585(CHEMBL3394049)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061586(CHEMBL3394050)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061588(CHEMBL3394052)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061598(CHEMBL3394045)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061893(CHEMBL3394212)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061890(CHEMBL3394211)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061874(CHEMBL3394210)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061835(CHEMBL3394228)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061831(CHEMBL3394227)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061738(CHEMBL3394224)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061737(CHEMBL3394223)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061736(CHEMBL3394222)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061735(CHEMBL3394221)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061734(CHEMBL3394220)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061733(CHEMBL3394219)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061732(CHEMBL3394218)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061731(CHEMBL3394217)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061730(CHEMBL3394216)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061965(CHEMBL3394213)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061728(CHEMBL3394214)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50061729(CHEMBL3394215)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061732(CHEMBL3394218)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061780(CHEMBL3394226)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061831(CHEMBL3394227)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061730(CHEMBL3394216)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061738(CHEMBL3394224)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061735(CHEMBL3394221)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061734(CHEMBL3394220)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50032737(CHEMBL3354718)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061775(CHEMBL3394225)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061890(CHEMBL3394211)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061835(CHEMBL3394228)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061731(CHEMBL3394217)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061893(CHEMBL3394212)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant BACE1 pre-incubated with enzyme for 60 mins before fluorescent substrate addition FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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