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TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517279(CHEMBL4456830)
Affinity DataEC50:  134nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50260268(rPKPfQwFwLL-NH2 | CHEMBL501261)
Affinity DataEC50:  99nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517283(CHEMBL425281)
Affinity DataEC50:  1.5nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataEC50:  2.5nMAssay Description:Antagonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in ghrelin-induced inositol phosphate production at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM22417(LY 94939 | Nisoxetine Inhibitor | Nisoxetine | LY1...)
Affinity DataKd:  5.10nMAssay Description:Binding affinity to human wild type NET expressed in african green monkey COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50396915(CHEMBL2170781)
Affinity DataEC50:  5.5nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517280(CHEMBL4463042)
Affinity DataEC50:  46nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517281(CHEMBL4517399)
Affinity DataEC50:  17nMAssay Description:Antagonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in ghrelin-induced inositol phosphate production at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517281(CHEMBL4517399)
Affinity DataEC50:  28nMAssay Description:Antagonist activity at human SNAP-tagged GHSR expressed in HEK293T cells assessed as reduction in ghrelin-induced calcium production at 1 uM by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517277(CHEMBL4541252)
Affinity DataEC50:  368nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517284(CHEMBL4581511)
Affinity DataEC50:  6.63E+3nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517278(CHEMBL4475293)
Affinity DataEC50:  48nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517281(CHEMBL4517399)
Affinity DataEC50:  23nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataEC50:  18nMAssay Description:Antagonist activity at human SNAP-tagged GHSR expressed in HEK293T cells assessed as reduction in ghrelin-induced calcium production at 1 uM by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataEC50:  76nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 0.184nMAssay Description:Inhibition of rat alpha1beta1epsilondelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit gamma(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547500(CHEMBL4759352)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit gamma(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547501(CHEMBL4788244)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat alpha6alpha3beta2beta3 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit gamma(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547503(CHEMBL4753712)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547501(CHEMBL4788244)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547503(CHEMBL4753712)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253820((1R,6R,9S,12S,15S,21S,24S,27S,30S,33R,36S,42S,48S,...)
Affinity DataIC50: 55nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50547500(CHEMBL4759352)
Affinity DataIC50: 68nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253824((1R,6R,9S,15S,18S,21S,24S,27R,30S,36S,42S,45S,50R)...)
Affinity DataIC50: 79nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253825((1R,6R,9S,12S,18S,21S,24S,27S,30R,33S,39S,45S,48S,...)
Affinity DataIC50: 115nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253823((1R,4S,10S,16S,19S,22R,27R,30S,33S,36S,39S,46R)-46...)
Affinity DataIC50: 207nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253821((1R,6R,9S,12S,15S,21S,24S,27S,30S,33R,36S,42S,48S,...)
Affinity DataIC50: 252nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253822((1R,4S,10S,16S,19S,22R,27R,30S,33S,36S,43R)-43-(2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at rat alpha7 nAChR expressed in Xenopus laevis assessed as inhibition of acetylcholine-induced current at holding potential of -80 mV by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517283(CHEMBL425281)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517281(CHEMBL4517399)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517280(CHEMBL4463042)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517278(CHEMBL4475293)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517279(CHEMBL4456830)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50396915(CHEMBL2170781)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517277(CHEMBL4541252)
Affinity DataKi:  6.5nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253820((1R,6R,9S,12S,15S,21S,24S,27S,30S,33R,36S,42S,48S,...)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50517284(CHEMBL4581511)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50260268(rPKPfQwFwLL-NH2 | CHEMBL501261)
Affinity DataKi:  77nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253821((1R,6R,9S,12S,15S,21S,24S,27S,30S,33R,36S,42S,48S,...)
Affinity DataKi:  124nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253825((1R,6R,9S,12S,18S,21S,24S,27S,30R,33S,39S,45S,48S,...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253823((1R,4S,10S,16S,19S,22R,27R,30S,33S,36S,39S,46R)-46...)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253824((1R,6R,9S,15S,18S,21S,24S,27R,30S,36S,42S,45S,50R)...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50253822((1R,4S,10S,16S,19S,22R,27R,30S,33S,36S,43R)-43-(2-...)
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed