Compile Data Set for Download or QSAR
Report error Found 78 with Last Name = 'feher' and Initial = 'va'
LigandPNGBDBM50321576(1-(4-(3-aminoazetidine-1-carbonyl)-5-(2-fluoro-4-i...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321561(1-acetyl-4-(2-fluoro-4-iodophenylamino)-N-(2-hydro...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321567((S)-5-acetyl-N-(2,3-dihydroxypropoxy)-2-(2-fluoro-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321577((R)-1-(5-(2-fluoro-4-iodophenylamino)-4-(3-hydroxy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321572((S)-5-acetyl-4-chloro-N-(2,3-dihydroxypropoxy)-2-(...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321564(5-acetyl-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hyd...)
Affinity DataIC50: 18nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50321570(5-acetyl-4-chloro-2-(2-fluoro-4-iodophenylamino)-N...)
Affinity DataIC50: 18nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321568(5-acetyl-N-(1,3-dihydroxypropan-2-yloxy)-2-(2-fluo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321574((S)-5-acetyl-N-(2,3-dihydroxypropoxy)-4-fluoro-2-(...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321562(1-acetyl-4-(2-fluoro-4-iodophenylamino)-N-(2-hydro...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321566((R)-5-acetyl-N-(2,3-dihydroxypropoxy)-2-(2-fluoro-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321573((R)-5-acetyl-N-(2,3-dihydroxypropoxy)-4-fluoro-2-(...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321575(1-(5-(2-fluoro-4-iodophenylamino)-4-(3-hydroxyazet...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321571((R)-5-acetyl-4-chloro-N-(2,3-dihydroxypropoxy)-2-(...)
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321563(5-acetyl-2-(2-fluoro-4-iodophenylamino)-1-methyl-1...)
Affinity DataIC50: 42nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321565(5-acetyl-2-(2-fluoro-4-iodophenylamino)-N-(3-hydro...)
Affinity DataIC50: 46nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321560(1-acetyl-4-(2-fluoro-4-iodophenylamino)-5-methyl-1...)
Affinity DataIC50: 72nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321569(5-acetyl-2-(2-fluoro-4-iodophenylamino)-N-(3-hydro...)
Affinity DataIC50: 90nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321559(1-acetyl-4-(2-fluoro-4-iodophenylamino)-1H-pyrrole...)
Affinity DataIC50: 220nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583310(CHEMBL5082711)
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583311(CHEMBL5084930)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583312(CHEMBL5076143)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583312(CHEMBL5076143)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583312(CHEMBL5076143)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583311(CHEMBL5084930)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583311(CHEMBL5084930)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 30 min in presence of NADPH by LC-LS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136934(3',4'-Dichloro-biphenyl-3-sulfonic acid (3-chloro-...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136916(3'-Chloro-4'-fluoro-biphenyl-3-sulfonic acid (3-ch...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136914(4'-Chloro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136919(3',4'-Difluoro-biphenyl-3-sulfonic acid (3-chloro-...)
Affinity DataKi:  8.10nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136913(N-(3-Chloro-7-isobutylamino-1H-indazol-5-yl)-3-qui...)
Affinity DataKi:  10.8nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136936(3'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)
Affinity DataKi:  11nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136942(4'-Chloro-biphenyl-3-sulfonic acid (3-chloro-7-iso...)
Affinity DataKi:  12.5nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136911(4'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)
Affinity DataKi:  13nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136918(4'-Fluoro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)
Affinity DataKi:  14.6nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136935(3'-Methylsulfanyl-biphenyl-3-sulfonic acid (3-chlo...)
Affinity DataKi:  17nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136910(3'-Trifluoromethyl-biphenyl-3-sulfonic acid (7-iso...)
Affinity DataKi:  20nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136943(3'-(2-Hydroxy-ethyl)-biphenyl-3-sulfonic acid (3-c...)
Affinity DataKi:  25nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 78 total ) | Next | Last >>
Jump to: