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TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19368(1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  56nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19369(1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19370(3-tert-butyl-1-(4-{2,4-diamino-6-[(benzyloxy)methy...)
Affinity DataEC50:  7nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19371(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  88nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19372(1-benzyl-3-(4-{2,4-diamino-6-[(benzyloxy)methyl]py...)
Affinity DataEC50:  34nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19373(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  10nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19374(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  7nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Abbott Laboratories

LigandPNGBDBM19352(6-ethyl-5-{1-[(4-methanesulfonylphenyl)methyl]-1H-...)
Affinity DatapH: 7.3 T: 2°CAssay Description:DHFR activity was determined by measuring the rate of depletion of NADPH, monitored at 340 nm, with a Beckman DU-7400 spectrophotometer. More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477256(CHEMBL436805)
Affinity DataEC50:  4.57E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477257(CHEMBL395452)
Affinity DataEC50:  1.70E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477258(CHEMBL393952)
Affinity DataEC50:  8.91E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477259(CHEMBL240768)
Affinity DataEC50:  3.72E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477260(CHEMBL238487)
Affinity DataEC50:  1.05E+4nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477261(CHEMBL240990)
Affinity DataEC50:  2.69E+4nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477262(CHEMBL238883)
Affinity DataEC50:  759nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477263(CHEMBL240988)
Affinity DataEC50:  3.80E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50413958(CHEMBL240177)
Affinity DataEC50:  9.77E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477264(CHEMBL241198)
Affinity DataEC50: <1.00E+5nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477265(CHEMBL393130)
Affinity DataEC50:  9.55E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477266(CHEMBL238639)
Affinity DataEC50:  4.27E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477267(CHEMBL241409)
Affinity DataEC50:  1.29E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477268(CHEMBL238699)
Affinity DataEC50:  1.20E+4nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477269(CHEMBL239119)
Affinity DataEC50:  813nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477270(CHEMBL240345)
Affinity DataEC50:  2.75E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477271(CHEMBL239514)
Affinity DataEC50:  457nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477272(CHEMBL393425)
Affinity DataEC50:  1.32E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477273(CHEMBL238422)
Affinity DataEC50:  2.04E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477274(CHEMBL238854)
Affinity DataEC50:  4.27E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50413959(CHEMBL540965)
Affinity DataEC50:  6.03E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477275(CHEMBL391369)
Affinity DataEC50:  537nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477276(CHEMBL238638)
Affinity DataEC50:  2.29E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477277(CHEMBL395175)
Affinity DataEC50:  2.24E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477278(CHEMBL395453)
Affinity DataEC50:  5.37E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477279(CHEMBL393730)
Affinity DataEC50:  1.18E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477280(CHEMBL274449)
Affinity DataEC50:  1.07E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477281(CHEMBL240766)
Affinity DataEC50:  2.09E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477282(CHEMBL240559)
Affinity DataEC50:  8.91E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477283(CHEMBL240347)
Affinity DataEC50:  5.37E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477284(CHEMBL240560)
Affinity DataEC50:  1.74E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM86249(ZD-6169 | ZD 6169)
Affinity DataEC50:  437nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477285(CHEMBL392290)
Affinity DataEC50:  6.76E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477286(CHEMBL393831)
Affinity DataEC50:  646nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477287(CHEMBL241410)
Affinity DataEC50:  1.66E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477288(CHEMBL239121)
Affinity DataEC50:  891nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477289(CHEMBL240989)
Affinity DataEC50:  7.76E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477290(CHEMBL397830)
Affinity DataEC50:  1.29E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477291(CHEMBL239090)
Affinity DataEC50:  1.62E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477292(CHEMBL238884)
Affinity DataEC50:  1.51E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477293(CHEMBL239128)
Affinity DataEC50:  912nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50477294(CHEMBL240131)
Affinity DataEC50:  2.04E+3nMAssay Description:Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
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