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TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50169955(3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50169955(3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363407(CHEMBL1946826)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(3-(2-aminoethyl)-5-(4-(dimethylamino)benzylidene)t...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324737(3-(2-aminoethyl)-5-(4-(dimethylamino)benzylidene)t...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50049243(5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...)
Affinity DataIC50:  225nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM26645((5Z)-5-[(4-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  228nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363409(CHEMBL1946828)
Affinity DataIC50:  242nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50363407(CHEMBL1946826)
Affinity DataIC50:  268nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)
Affinity DataIC50:  298nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363411(CHEMBL596254)
Affinity DataIC50:  305nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350498(CHEMBL1814650)
Affinity DataIC50:  520nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50363411(CHEMBL596254)
Affinity DataIC50:  709nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50350503(CHEMBL1814645)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50:  832nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  860nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Rat)
Northeastern Ohio Universities

Curated by ChEMBL
LigandPNGBDBM50350486(CHEMBL602048)
Affinity DataIC50:  900nMAssay Description:Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363405(CHEMBL1946644)
Affinity DataIC50:  921nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50363409(CHEMBL1946828)
Affinity DataIC50:  979nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Rat)
Northeastern Ohio Universities

Curated by ChEMBL
LigandPNGBDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50350493(CHEMBL1814644)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50169955(3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Rat)
Northeastern Ohio Universities

Curated by ChEMBL
LigandPNGBDBM50030474(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50340098(5-(4-hydroxy-3-methoxybenzylidene)-2-thioxothiazol...)
Affinity DataIC50:  1.73E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50350486(CHEMBL602048)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50340098(5-(4-hydroxy-3-methoxybenzylidene)-2-thioxothiazol...)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM49448(MLS000534832 | N-(4-methoxyphenyl)-1-indolinecarbo...)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50352038(CHEMBL1823806)
Affinity DataIC50:  2.93E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50324735((5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE...)
Affinity DataIC50:  3.26E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50363408(CHEMBL1946827)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50322615(CHEMBL1173685 | CHEMBL1823816 | Resveratrol Potass...)
Affinity DataIC50:  3.36E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50324738(3-(5-benzylidene-2,4-dioxothiazolidin-3-yl)propane...)
Affinity DataIC50:  3.49E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350492(CHEMBL1814643)
Affinity DataIC50:  4.47E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350502(CHEMBL1814651)
Affinity DataIC50:  4.98E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50352037(CHEMBL1823804)
Affinity DataIC50:  5.23E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50363405(CHEMBL1946644)
Affinity DataIC50:  5.36E+3nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350504(CHEMBL1814639)
Affinity DataIC50:  5.97E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50324737(3-(2-aminoethyl)-5-(4-(dimethylamino)benzylidene)t...)
Affinity DataIC50:  6.88E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350486(CHEMBL602048)
Affinity DataIC50:  7.36E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350487(CHEMBL1814635)
Affinity DataIC50:  9.56E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350490(CHEMBL1814638)
Affinity DataIC50:  9.63E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50350498(CHEMBL1814650)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350503(CHEMBL1814645)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50350489(CHEMBL1814637)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50324741(2-(2,4-dioxothiazolidin-5-yl)-N-(3-hydroxyphenyl)a...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Human)
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50350497(CHEMBL1814649)
Affinity DataIC50:  1.11E+4nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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