Report error Found 352 with Last Name = 'gagne' and Initial = 'd'
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataKd: 1.62E+4nMAssay Description:Binding affinity to SIRT1More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 4.62E+4nMAssay Description:Activation of human SIRT1 expressed in Escherichia coli BL21 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 82nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sirtris Pharmaceuticals
Curated by ChEMBL
Sirtris Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sirtris Pharmaceuticals
Curated by ChEMBL
Sirtris Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Inverse agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+3nMAssay Description:Activation of human SIRT1 expressed in Escherichia coli BL21 by mass spectrometry assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sirtris Pharmaceuticals
Curated by ChEMBL
Sirtris Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 64nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sirtris Pharmaceuticals
Curated by ChEMBL
Sirtris Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT3 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.62E+4nMAssay Description:Binding affinity to human SIRT1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Activation of human SIRT1 expressed in Escherichia coli BL21 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inverse agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at human GHS1a receptor expressed in CHO cells assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 360nMAssay Description:Activation of human SIRT1 expressed in Escherichia coli BL21 by mass spectrometry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nM EC50: 3nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nM EC50: 0.600nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nM EC50: 1.60nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of 125I-[His9]-ghrelin from human GHSR1a expressed in LLC-PK1 cells by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nM EC50: 6.10nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair






3D Structure (crystal)





























