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LigandPNGBDBM762547(2-[[6-(5-amino-4-methyl-3-pyridyl)-7-fluoro-3- iso...)
Affinity DataKi:  0.0100nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762563(tert-butyl 7-[7-fluoro-3-[(6-methyl-7-oxo-5,8- dih...)
Affinity DataKi:  0.0100nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598166(US11612606, Compound 522a | (1R,5S,6s)-3-(Methylsu...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762605(2-((6-(5-amino-4-methylpyridin-3-yl)-7- fluoroisoq...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598170(US11612606, Compound 525a | (1s,3s)-3-(3-Fluoroaze...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762604(N-(6-(5-amino-4-methylpyridin-3-yl)-7- fluoroisoqu...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598177(US11612606, Compound 528a | (1s,3s)-3-Methoxy-3-me...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598150(US11612606, Compound 511a | (R)-8-(Oxetan-3-yl)-8-)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598155(US11612606, Compound 514a | (1r,3r)-3-(1H-Imidazol...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598153(US11612606, Compound 512b | (1r,3s)-3-Ethyl-3-hydr...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598160(US11612606, Compound 517a | (1s,3s)-3-(Azetidine-1...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762606(2-((6-(5-amino-4-methylpyridin-3-yl)-7- fluoroisoq...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598159(US11612606, Compound 516b | (3R,4S)-4-Cyclopropylt...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762609(fluoroisoquinolin-3-yl)amino)-6-(tert-butyl)-4- | ...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598164(US11612606, Compound 520a | (1s,3s)-3-(Methylcarba...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598197(US11612606, Compound 539a | (1r,3r)-3-(Methylamino...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598204(US11612606, Compound 543a | (1R,5S,6s)-3-Oxabicycl...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762625(N-(7-fluoro-6-(9-methyl-1,2,3,4- tetrahydropyrido[...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598210(US11612606, Compound 546a | trans-4-Methoxytetrahy...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762647((R)-2'-((7-fluoro-6-(8-hydroxy-4-methyl- | US12378...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762648(5,6,7,8-tetrahydro-1,5-naphthyridin-3- | US1237824...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762573(2-((7,8-difluoro-6-(8-methyl-2,3-dihydro-1H- pyrid...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598192(US11612606, Compound 536b | (1s,3r)-3-(Cyanomethyl...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598191(US11612606, Compound 536a | (1r,3s)-3-(Cyanomethyl...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598189(US11612606, Compound 535a | trans-2-Cyanocyclobuty...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598194(US11612606, Compound 537b | (1r,3r)-3-Cyano-3-meth...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598232(US11612606, Compound 559d | (1S,2S)-2-Methylcyclob...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598231(US11612606, Compound 559c | trans-2-Methylcyclobut...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762584(1H-pyrido[2,3-b][1,4]oxazin-7-yl)isoquinolin- | US...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762585((S)-2-((7-fluoro-6-(8-methyl-2,3-dihydro-1H- | US1...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762586(pyrido[2,3-b][1,4]oxazin-7-yl)isoquinolin-3- | US1...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762669(2'-((6-(5-amino-4-methylpyridin-3-yl)-8- fluoroiso...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762668(2'-((6-(5-amino-4-methylpyridin-3-yl)-7- fluoroiso...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762590(N-(7-fluoro-6-(8-methyl-2,3-dihydro-1H- pyrido[2,3...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762579(N-(7-fluoro-6-(8-methyl-2,3-dihydro-1H- pyrido[2,3...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762581(2-((7-fluoro-6-(8-methyl-2,3-dihydro-1H- pyrido[2,...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598216(US11612606, Compound 550a | (1r,3r)-3-Morpholinocy...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598215(US11612606, Compound 549b | (1r,3r)-3-(2-Cyanoprop...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598214(US11612606, Compound 549a | (1s,3s)-3-(2-Cyanoprop...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598220(US11612606, Compound 553a | (1s,3s)-3-hydroxycyclo...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598218(US11612606, Compound 551a | (1s,3s)-3-Cyclopropyl-...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598223(US11612606, Compound 555b | (3R,4S)-4-Methyltetrah...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598222(US11612606, Compound 555a | trans-4-Methyltetrahyd...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM762601(2-((7-fluoro-6-(8-methyl-2,3-dihydro-1H- pyrido[2,...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM598226(US11612606, Compound 557a | (1s,3s)-3-Cyanocyclobu...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598225(US11612606, Compound 556b | (3R,4S)-4-Methyltetrah...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM598264(US11612606, Compound 580 | 7-Azaspiro[3.5]nonan-2-...)
Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent

LigandPNGBDBM591155(US11566003, Compound 111)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandPNGBDBM762697((S)-7-(3-((5,6-dihydro-11H-imidazo[1,2- | US123782...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM762699(2-((7-fluoro-6-(8-methyl-2,3-dihydro-1H- | US12378...)
Affinity DataKi:  0.0130nMAssay Description:Assay Condition:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
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