Report error Found 80 with Last Name = 'gruber' and Initial = 'jm'
Affinity DataEC50: 900nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.47E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.13E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.77E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90E+3nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibitory activity against MRP1 in HeLa-T5 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Inhibitory activity against MRP1 in HeLa-T5 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Inhibitory activity against MRP1 in HeLa-T5 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Inhibitory activity against MRP1 in HeLa-T5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged autotaxin expressed in human 293E cells assessed as choline release using lysophosp...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against MRP1-mediated LTC4 uptake into membrane vesicles from HeLa-T5 cells expressing MRP1More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of autotaxin in healthy human plasma assessed as reduction in LPA level after 3 hrs by mass spectrometric analysisMore data for this Ligand-Target Pair
