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Report error Found 213 with Last Name = 'hartung' and Initial = 'i'
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181512(CHEMBL3819277 | US10023539, Example WO 2006/07235...)
Affinity DataKd:  540nMAssay Description:Binding affinity to SMYD2 (unknown origin) by isothermal colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254841(US9487554, 28)
Affinity DataIC50: 0.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254826(US9487554, 13)
Affinity DataIC50: 0.800nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254825(US9487554, 12)
Affinity DataIC50: 1.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254815(US9487554, 2)
Affinity DataIC50: 1.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254814(US9487554, 1)
Affinity DataIC50: 1.40nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254815(US9487554, 2)
Affinity DataIC50: 1.40nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254825(US9487554, 12)
Affinity DataIC50: 1.70nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254824(US9487554, 11)
Affinity DataIC50: 1.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254826(US9487554, 13)
Affinity DataIC50: 1.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM50134989(CHEMBL3746640)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254814(US9487554, 1)
Affinity DataIC50: 1.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254836(US9487554, 23)
Affinity DataIC50: 1.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254824(US9487554, 11)
Affinity DataIC50: 2.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254842(US9487554, 29)
Affinity DataIC50: 2.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254818(US9487554, 5)
Affinity DataIC50: 3.60nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254835(US9487554, 22)
Affinity DataIC50: 4.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254818(US9487554, 5)
Affinity DataIC50: 4.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254829(US9487554, 16)
Affinity DataIC50: 4.40nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254823(US9487554, 10)
Affinity DataIC50: 4.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254837(US9487554, 24)
Affinity DataIC50: 5.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254821(US9487554, 8)
Affinity DataIC50: 6.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254828(US9487554, 15)
Affinity DataIC50: 6.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254829(US9487554, 16)
Affinity DataIC50: 6.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM104963(CHEMBL507361 | US8575391, Q | US11147816, PD032590...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254828(US9487554, 15)
Affinity DataIC50: 7.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254823(US9487554, 10)
Affinity DataIC50: 7.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254843(US9487554, 30)
Affinity DataIC50: 7.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254818(US9487554, 5)
Affinity DataIC50: 8nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254822(US9487554, 9)
Affinity DataIC50: 8.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254820(US9487554, 7)
Affinity DataIC50: 8.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254821(US9487554, 8)
Affinity DataIC50: 8.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254834(US9487554, 21)
Affinity DataIC50: 8.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM50134989(CHEMBL3746640)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu-ADR matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254817(US9487554, 4)
Affinity DataIC50: 8.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254822(US9487554, 9)
Affinity DataIC50: 8.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254822(US9487554, 9)
Affinity DataIC50: 8.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254818(US9487554, 5)
Affinity DataIC50: 9.10nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254816(US9487554, 3)
Affinity DataIC50: 9.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254820(US9487554, 7)
Affinity DataIC50: 9.60nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254827(US9487554, 14)
Affinity DataIC50: 9.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM50134978(CHEMBL3747294)
Affinity DataIC50: 10nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181506(CHEMBL3819038)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254816(US9487554, 3)
Affinity DataIC50: 10.2nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254839(US9487554, 26)
Affinity DataIC50: 11nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM50134968(CHEMBL3746569)
Affinity DataIC50: 11nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254843(US9487554, 30)
Affinity DataIC50: 11.2nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM50134971(CHEMBL3747066)
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
LigandPNGBDBM50490986(CHEMBL2376674)
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50134976(CHEMBL3746736)
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
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