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TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310316(2-((6S,9S)-6-((1H-indol-3-yl)methyl)-13,16-dibenzy...)
Affinity DataEC50:  1.68E+3nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310325(2-((6S,9S,12R)-6-((1H-indol-3-yl)methyl)-12,16-dib...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310323((S)-2-((R)-2-(2-(2-acetamido-N-benzylacetamido)ace...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374672(CHEMBL271586)
Affinity DataEC50:  7.75E+3nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310314(2-((6S,9S)-6-((1H-indol-3-yl)methyl)-13,16-dibenzy...)
Affinity DataEC50:  990nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374670(CHEMBL270923)
Affinity DataEC50:  390nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310317(2-((6S,9S,15S)-6-((1H-indol-3-yl)methyl)-13,15-dib...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  130nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKd:  2.17E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374672(CHEMBL271586)
Affinity DataEC50:  240nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50497213(CHEMBL3289502)
Affinity DataEC50:  3.18E+4nMAssay Description:Modulation of GABAA alpha1beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chlorid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310320(2-((6S,9S,15S)-6-((1H-indol-3-yl)methyl)-13,15-dib...)
Affinity DataEC50:  3.96E+3nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataEC50:  6.72E+4nMAssay Description:Modulation of GABAA alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374669(CHEMBL406985)
Affinity DataEC50:  18nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310316(2-((6S,9S)-6-((1H-indol-3-yl)methyl)-13,16-dibenzy...)
Affinity DataEC50:  2.25E+3nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465105(CHEMBL1235691)
Affinity DataKd:  320nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374671(CHEMBL272660)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKd:  2.10E+5nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374670(CHEMBL270923)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465105(CHEMBL1235691)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50497215(CHEMBL3289482)
Affinity DataEC50:  5.53E+4nMAssay Description:Modulation of GABAA alpha1beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chlorid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKd:  2.17E+3nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310318(2-((6S,9S,12R)-6-((1H-indol-3-yl)methyl)-12,16-dib...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0970nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310318(2-((6S,9S,12R)-6-((1H-indol-3-yl)methyl)-12,16-dib...)
Affinity DataEC50:  640nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)
Affinity DataKd:  8.80E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465106(CHEMBL3392935)
Affinity DataKd:  340nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374669(CHEMBL406985)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50497207(CHEMBL3289501)
Affinity DataEC50:  1.02E+5nMAssay Description:Modulation of GABAA alpha1beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chlorid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310322((S)-2-(2-((S)-2-(2-acetamidoacetamido)-N-benzyl-3-...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50497208(CHEMBL3289196)
Affinity DataEC50:  2.95E+4nMAssay Description:Modulation of GABAA alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as modulation of GABA-induced chloride ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to Influenza A virus M2 transmembrane domain by analytical ultracentrifugation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310324(Phe-D-Phe-Arg-Trp-NH2 | CHEMBL589515)
Affinity DataEC50:  1.19E+4nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310318(2-((6S,9S,12R)-6-((1H-indol-3-yl)methyl)-12,16-dib...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.0630nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465105(CHEMBL1235691)
Affinity DataKd:  320nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465106(CHEMBL3392935)
Affinity DataKd:  340nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 4(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310315(2-((6S,9S,15S)-6-((1H-indol-3-yl)methyl)-13,15-dib...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374673(CHEMBL408398)
Affinity DataEC50:  7nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)
Affinity DataKd:  1.80E+6nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM246487(Batatasin III (4) | US20240398793, Compound 8)
Affinity DataEC50:  8.08E+4nMAssay Description:Modulation of GABAA alpha2beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310321(2-((6S,9S,12R)-6-((1H-indol-3-yl)methyl)-12,16-dib...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374673(CHEMBL408398)
Affinity DataEC50:  64nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataKd:  16nMAssay Description:Binding affinity to TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374669(CHEMBL406985)
Affinity DataEC50:  1.46E+3nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50374673(CHEMBL408398)
Affinity DataEC50:  770nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310319(2-((6S,9S)-6-((1H-indol-3-yl)methyl)-13,16-dibenzy...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50310323((S)-2-((R)-2-(2-(2-acetamido-N-benzylacetamido)ace...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
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