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TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50140257(CHEMBL16171 | 5,7-Dihydroxy-8-methoxy-2-phenyl-chr...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254327(2-(2,4-dimethoxyphenyl)-6-(4-oxo-2-phenyl-4H-chrom...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254381(2-(4-methoxyphenyl)-6-(4-oxo-2-phenyl-4H-chromen-7...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50257785(5,7-diacetylflavone | CHEMBL493969)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183248(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183250(CHEMBL187504 | 2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50257725(2,3-dimethoxy-2'-hydroxychalcone | CHEMBL492959)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50241204((E)-3-(4-(benzyloxy)phenyl)-1-(2-hydroxyphenyl)pro...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50257724(3,4-dibenzyloxy-2'-hydroxychalcone | CHEMBL492554)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183248(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50257726(2'-hydroxy-3,4,5-trimethoxychalcone | CHEMBL521653)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183244(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50253965(2-(4-hydroxyphenyl)-7-(2-(2-hydroxyphenyl)-4-oxo-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254380(6,7'-oxybis(2-(2,4-dihydroxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254380(6,7'-oxybis(2-(2,4-dihydroxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183245([6,4''']biflavone | 6-[4-(4-Oxo-4H-chromen-2-yl)-p...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183247(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183246(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183246(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183244(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183246(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of human cloned sPLA2-10 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183247(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183249([6,6'']biflavone | 2,2'-Diphenyl-[6,6']bichromenyl...)
Affinity DataIC50: 4.81E+4nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50253965(2-(4-hydroxyphenyl)-7-(2-(2-hydroxyphenyl)-4-oxo-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254285(6,7'-oxybis(2-phenyl-4H-chromen-4-one) | CHEMBL466...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254424(2-(2-hydroxyphenyl)-6-(4-oxo-2-phenyl-4H-chromen-7...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254423(2-(2-methoxyphenyl)-6-(4-oxo-2-phenyl-4H-chromen-7...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254422(2-(2,4-dihydroxyphenyl)-7-(2-(4-hydroxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254383(2-(2,4-dimethoxyphenyl)-7-(2-(4-methoxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254382(6,7'-oxybis(2-(4-hydroxyphenyl)-4H-chromen-4-one) ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254331(6,7'-oxybis(2-(2,4-dimethoxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254330(2-(2,4-dihydroxyphenyl)-6-(2-(4-hydroxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254329(2-(2,4-dimethoxyphenyl)-6-(2-(4-methoxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Medicine and Pharmacy At Ho Chi Minh City

Curated by ChEMBL
LigandPNGBDBM50254328(2-(2,4-dihydroxyphenyl)-6-(4-oxo-2-phenyl-4H-chrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254422(2-(2,4-dihydroxyphenyl)-7-(2-(4-hydroxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254383(2-(2,4-dimethoxyphenyl)-7-(2-(4-methoxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254331(6,7'-oxybis(2-(2,4-dimethoxyphenyl)-4H-chromen-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254330(2-(2,4-dihydroxyphenyl)-6-(2-(4-hydroxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50254329(2-(2,4-dimethoxyphenyl)-6-(2-(4-methoxyphenyl)-4-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells by Griess methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183245([6,4''']biflavone | 6-[4-(4-Oxo-4H-chromen-2-yl)-p...)
Affinity DataIC50: 6.39E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50183249([6,6'']biflavone | 2,2'-Diphenyl-[6,6']bichromenyl...)
Affinity DataIC50: 6.93E+4nMAssay Description:Inhibition of sPLA2-2A in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Rat)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183246(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat cloned sPLA2-1B expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Rat)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183248(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat cloned sPLA2-1B expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosolic phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183250(CHEMBL187504 | 2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cloned cPLA2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Rat)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183247(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat cloned sPLA2-1B expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183250(CHEMBL187504 | 2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cloned sPLA2-10 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50183244(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cloned sPLA2-10 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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