Compile Data Set for Download or QSAR
Report error Found 1354 with Last Name = 'kim' and Initial = 'hr'
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515218(CHEMBL4538994)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50405727(CHEMBL2115031)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataEC50:  260nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515219(CHEMBL4456225)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515222(CHEMBL4589829)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515225(CHEMBL4464364)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515224(CHEMBL4473818)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515226(CHEMBL4476535)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515221(CHEMBL4538845)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515228(CHEMBL4591427)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50088426(3-(6-Amino-purin-9-yl)-5-hydroxymethyl-cyclopentan...)
Affinity DataEC50:  640nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515227(CHEMBL4465968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515223(CHEMBL4522602)
Affinity DataEC50:  1.75E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50555362(CHEMBL4748172)
Affinity DataEC50:  2.64E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632630(CHEMBL5427431)
Affinity DataEC50:  1.63E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632633(CHEMBL5406591)
Affinity DataEC50:  2.91E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632636(CHEMBL5431536)
Affinity DataEC50:  2.25E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632641(CHEMBL5431290)
Affinity DataEC50:  6.52E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632644(CHEMBL5397940)
Affinity DataEC50:  1.14E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  3.62E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50310204(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataEC50:  6.69E+4nMAssay Description:Inhibition of human PDE4D in U937 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50310217(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataEC50:  1.61E+3nMAssay Description:Inhibition of human PDE4D in U937 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512366(US11084824, Example 21)
Affinity DataIC50: 0.200nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHepatocyte growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384024(CHEMBL2032280 | CHEMBL2079349)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243386(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)
Affinity DataIC50: 0.210nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243393(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)
Affinity DataIC50: 0.240nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243402(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of crizotinib-resistant ALK G1269A mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor [L1196M](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243393(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243395(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512364(Preparation of N3-(2,6-dimethylphenyl)-N6-(1,2,3,4...)
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512368(US11084824, Example 23)
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512369(US11084824, Example 24)
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512370(US11084824, Example 25)
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50380974(CHEMBL2016903)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50240271(CHEMBL4101954)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of wild type ALK (unknown origin) using TK as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50116683(US10053458, 49 | CHEMBL3608526)
Affinity DataIC50: 0.380nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512367(US11084824, Example 22)
Affinity DataIC50: 0.400nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM291934(US10100019, Example 4)
Affinity DataIC50: 0.440nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243402(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of crizotinib-resistant ALK C1156Y mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243402(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of crizotinib-resistant ALK F1174L mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512363(US11084824, Example 18)
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512351(US11084824, Example 2 | US11084824, Example 20)
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50380971(CHEMBL2016927)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50157303(CHEMBL3785774)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50116690(US10053458, 67 | CHEMBL3608528)
Affinity DataIC50: 0.520nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512388(US11084824, Example 53)
Affinity DataIC50: 0.523nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243386(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50116696(US10053458, 52 | CHEMBL3608534)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512350(US11084824, Example 1)
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512351(US11084824, Example 2 | US11084824, Example 20)
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Displayed 1 to 50 (of 1354 total ) | Next | Last >>
Jump to: