Report error Found 1530 with Last Name = 'kim' and Initial = 'yc'
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 5.90E+3nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Mouse)
Gwangju Institute of Science and Technology (Gist)
Curated by ChEMBL
Gwangju Institute of Science and Technology (Gist)
Curated by ChEMBL
Affinity DataEC50: 186nMAssay Description:Inhibition of JAK2 V617F mutant expressed in mouse BaF3 cells cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 5.90E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataKd: <0.25nMAssay Description:Binding affinity to human FLT3 ITD mutant in presence of ATP by Lanthascreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataKd: 0.0154nMAssay Description:Binding affinity to FLT3 ITD/F691L double mutant (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gwangju Insitute of Science and Technology (Gist)
Curated by ChEMBL
Gwangju Insitute of Science and Technology (Gist)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of hERG incubated for 2 hrs by fluorescence polarization based assayMore data for this Ligand-Target Pair
TargetChemerin-like receptor 1(Human)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Antagonist activity at human CMKLR1More data for this Ligand-Target Pair
Affinity DataEC50: 7.21E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 651nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 1.98E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 6.49E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 6.29E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 1.71E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 1.22E+4nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 4.44E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 2.34E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 2.99E+3nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 2.77E+4nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Concentration at which 50% of the maximal effect (stimulation of PLC at P2Y1 receptor in the turkey erythrocyte membranes) is reachedMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+4nMAssay Description:Agonist activity at Drosophila melanogaster RYamide receptor expressed in wild type CHO-K1 cells assessed as increase in calcium level after 20 secs ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.90E+3nMAssay Description:Agonist activity at Drosophila melanogaster RYamide receptor expressed in wild type CHO-K1 cells assessed as increase in calcium level after 20 secs ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.80E+3nMAssay Description:Agonist activity at Drosophila melanogaster RYamide receptor expressed in wild type CHO-K1 cells assessed as increase in calcium level after 20 secs ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Agonist activity at Drosophila melanogaster RYamide receptor expressed in wild type CHO-K1 cells assessed as increase in calcium level after 20 secs ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00830nMAssay Description:Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage cl...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0481nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Antagonist activity at human P2X7 receptor in LPS/IFN-gamma-differentiated human THP-1 cells assessed as suppression of BzATP-stimulated IL-1beta rel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Antagonist activity at human P2X7 receptor in expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake measured after 2 hrs by fluo...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake measured after 2 hrs by fluo...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of FLT3 expressed in human SEMK2 cells assessed as reduction in FLT3 phosphorylation incubated for 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Antagonist activity at human P2X7 receptor in LPS/IFN-gamma-differentiated human THP-1 cells assessed as suppression of BzATP-stimulated IL-1beta rel...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human FLT3 D835Y mutant in presence of ATPMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake measured after 2 hrs by fluo...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
