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TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  8nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataEC50:  961nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466692(CHEMBL4286980)
Affinity DataEC50:  1.72E+3nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466688(CHEMBL4276678)
Affinity DataEC50:  172nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466689(CHEMBL4284250)
Affinity DataEC50:  1.74E+3nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466690(CHEMBL4293295)
Affinity DataEC50:  271nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataEC50:  657nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataEC50:  98nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 112nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50150998(2-[(4-methoxyphenoxycarbonyl)({4-[2-(5-methyl-2-ph...)
Affinity DataIC50: 120nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataIC50: 370nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitochondrial pyruvate carrier 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitochondrial pyruvate carrier 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataIC50: 1.79E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466688(CHEMBL4276678)
Affinity DataIC50: 2.32E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466690(CHEMBL4293295)
Affinity DataIC50: 3.12E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50103636(CHEBI:64227 | ADD-3878 | Ciglitazone | U-63287)
Affinity DataIC50: 5.00E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466693(CHEMBL4288064)
Affinity DataIC50: 8.46E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466691(CHEMBL4280830)
Affinity DataIC50: 1.17E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 1.81E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 2.23E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466689(CHEMBL4284250)
Affinity DataIC50: 5.01E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM50466692(CHEMBL4286980)
Affinity DataIC50: 7.85E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandPNGBDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed