Compile Data Set for Download or QSAR
Report error Found 1362 with Last Name = 'kong' and Initial = 'j'
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505272(CHEMBL4483362)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505276(CHEMBL4540823)
Affinity DataEC50:  1.12E+3nMAssay Description:Inhibition of HIV1 gp120 assessed as increase in anti-DNP binding to immobilized HIV-1 gp120 incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505277(CHEMBL4553027)
Affinity DataEC50:  570nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505278(CHEMBL4578515)
Affinity DataEC50:  500nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50501285(CHEMBL3937452)
Affinity DataEC50:  280nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505280(CHEMBL4528039)
Affinity DataEC50: >1.20E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505273(CHEMBL3800574)
Affinity DataEC50:  3.79E+4nMAssay Description:Inhibition of HIV1 gp120 assessed as increase in anti-DNP binding to immobilized HIV-1 gp120 incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50514847(CHEMBL4558745)
Affinity DataKd:  3.07E+3nMAssay Description:Binding affinity to AIMP2 D2X isoform (unknown origin) by fluorescence-based equilibrium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515218(CHEMBL4538994)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50405727(CHEMBL2115031)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataEC50:  260nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515219(CHEMBL4456225)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515222(CHEMBL4589829)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515225(CHEMBL4464364)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515224(CHEMBL4473818)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515226(CHEMBL4476535)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515221(CHEMBL4538845)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515228(CHEMBL4591427)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50088426(3-(6-Amino-purin-9-yl)-5-hydroxymethyl-cyclopentan...)
Affinity DataEC50:  640nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515227(CHEMBL4465968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515223(CHEMBL4522602)
Affinity DataEC50:  1.75E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122926(3-Amino-5-{6-[5-chloro-2-(3-methyl-isoxazol-5-ylme...)
Affinity DataEC50:  3.40nMAssay Description:Inhibition of isoproterenol-stimulated cAMP accumulation in HEK 293 cells expressing human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118812(CHEMBL119709 | (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-io...)
Affinity DataEC50:  1nMAssay Description:Inhibition of isoproterenol-stimulated cAMP accumulation in HEK 293 cells expressing human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182324((2S,3S,4R,5R)-5-(6-(5-chloro-2-(2-oxo-2-(piperazin...)
Affinity DataEC50:  8.10nMAssay Description:Inhibition of isoproterenol-induced increase of cAMP in HEK293 cell expressing human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304819(4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine | C...)
Affinity DataEC50:  755nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304803((R)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)
Affinity DataEC50:  120nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304815(4-(piperazin-1-yl)thieno[3,2-d]pyrimidine | CHEMBL...)
Affinity DataEC50:  400nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304807((S)-7-(5-fluoro-2-methylbenzyloxy)-2-((R)-2-methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity against 5HT2B receptor assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304813(6-bromo-8-(piperazin-1-yl)imidazo[1,2-a]pyrazine |...)
Affinity DataEC50:  1.36E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304809(4-(3-chlorobenzyloxy)-2-(piperazin-1-yl)thieno[2,3...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304820(2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinoline | C...)
Affinity DataEC50:  25nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016970(CHEMBL608135 | CHEMBL552833 | 4-Piperazin-1-yl-thi...)
Affinity DataEC50:  187nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304806((R)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  22nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304801((S)-7-(2,5-difluorobenzyloxy)-2-((R)-2-methylpiper...)
Affinity DataEC50:  1nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304800((S)-7-(2,5-difluorobenzyloxy)-2-(piperazin-1-yl)-6...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity against human 5HT2A receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304801((S)-7-(2,5-difluorobenzyloxy)-2-((R)-2-methylpiper...)
Affinity DataEC50:  1.43E+3nMAssay Description:Agonist activity against human 5HT2A receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304802((S)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)
Affinity DataEC50:  397nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304803((R)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)
Affinity DataEC50:  998nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304804(7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dihydro...)
Affinity DataEC50:  187nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  300nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304806((R)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)
Affinity DataEC50:  748nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304800((S)-7-(2,5-difluorobenzyloxy)-2-(piperazin-1-yl)-6...)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity against human 5HT2B receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304808(4-chloro-2-(piperazin-1-yl)thieno[2,3-d]pyrimidine...)
Affinity DataEC50:  616nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304810(4-(piperazin-1-yl)thieno[2,3-d]pyrimidine | CHEMBL...)
Affinity DataEC50:  530nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304811(6-methyl-4-(piperazin-1-yl)furo[2,3-d]pyrimidine |...)
Affinity DataEC50:  660nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304812(4-methoxy-2-(piperazin-1-yl)-5,6,7,8-tetrahydroqui...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016972(CHEMBL595555 | CHEMBL543969 | 4-Piperazin-1-yl-fur...)
Affinity DataEC50:  164nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304817(6-(piperazin-1-yl)-9-propyl-9H-purine | CHEMBL5944...)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304818(4-(3-chlorobenzyloxy)-2-(piperazin-1-yl)thieno[3,2...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304802((S)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)
Affinity DataEC50:  10nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 1362 total ) | Next | Last >>
Jump to: