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TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20164(CHEMBL434302 | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)...)
Affinity DataEC50:  460nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20174((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-di...)
Affinity DataEC50:  670nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20175((1S,2R,5S,10S,11S,14S,15S)-14-[(2S)-2-hydroxy-6-me...)
Affinity DataEC50:  470nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataEC50:  325nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20178((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4S)-4-hydroxy-6...)
Affinity DataEC50:  5.90E+3nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20179((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4R)-4-hydroxy-6...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20180((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5S)-5-hydroxy-6...)
Affinity DataEC50:  130nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20181((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5R)-5-hydroxy-6...)
Affinity DataEC50:  220nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataEC50:  1.16E+3nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20183((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,6R)-7-hydroxy-6...)
Affinity DataEC50:  250nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20184((2R)-2-[(2R)-2-[(1S,2R,5S,10S,11S,14R,15R)-5-hydro...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20185((6R)-6-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  180nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  170nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20187((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  720nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20188(N-[(2S)-2-[(1S,2R,5S,10S,11S,14R,15S)-5-hydroxy-2,...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20189(1-[(2S)-2-[(1S,2R,5S,10S,11S,14R,15S)-5-hydroxy-2,...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20190((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  3.00E+3nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20191(methyl (4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydrox...)
Affinity DataEC50:  105nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  5.50E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28700(alpha-1081 | procetofenic acid | Fenofibrate | CHE...)
Affinity DataEC50:  3.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28701(Cedur | 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}p...)
Affinity DataEC50:  5.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  1.89E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28702(2-[2-methyl-4-(2-{4-methyl-2-[4-(trifluoromethyl)p...)
Affinity DataEC50:  2.00E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28703(2-methyl-2-[4-(2-{4-methyl-2-[4-(trifluoromethyl)p...)
Affinity DataEC50:  210nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28704(2-methyl-2-[4-({4-methyl-2-[4-(trifluoromethyl)phe...)
Affinity DataEC50:  9.50E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28705(2-methyl-2-(4-{[({4-methyl-2-[4-(trifluoromethyl)p...)
Affinity DataEC50:  70nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28706(CHEMBL219586 | 2-methyl-2-{4-[({4-methyl-2-[4-(tri...)
Affinity DataEC50:  4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28707(2-methyl-2-{4-[(N-methyl{4-methyl-2-[4-(trifluorom...)
Affinity DataEC50:  240nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28708(2-methyl-2-{4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  1.32E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28709(2-methyl-2-{4-[2-({4-methyl-2-[4-(trifluoromethyl)...)
Affinity DataEC50:  110nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  5nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28711(2-methyl-2-{4-[({4-methyl-2-[4-(trifluoromethoxy)p...)
Affinity DataEC50:  4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28712(2-[4-({[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-...)
Affinity DataEC50:  10nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28713(2-methyl-2-[4-({[4-methyl-2-(4-nitrophenyl)-1,3-th...)
Affinity DataEC50:  30nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28714(2-[4-({[2-(4-methoxyphenyl)-4-methyl-1,3-thiazol-5...)
Affinity DataEC50:  10nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28715(2-[4-({[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-...)
Affinity DataEC50:  40nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28716(2-methyl-2-(4-{[(4-methyl-2-phenyl-1,3-thiazol-5-y...)
Affinity DataEC50:  120nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28717(2-methyl-2-{4-[({4-methyl-2-[3-(trifluoromethyl)ph...)
Affinity DataEC50:  4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28718(2-methyl-2-{4-[({4-methyl-2-[2-(trifluoromethyl)ph...)
Affinity DataEC50:  465nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28719(2-[4-({[2-(4-aminophenyl)-4-methyl-1,3-thiazol-5-y...)
Affinity DataEC50:  5.64E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28720(2-{4-[({2-[4-(methanesulfonyloxy)phenyl]-4-methyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28721(2-[4-({[2-(4-hydroxyphenyl)-4-methyl-1,3-thiazol-5...)
Affinity DataEC50: >1.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28722(2-methyl-2-{4-[({5-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataEC50:  1.89E+3nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28723(2-methyl-2-[4-({[4-(trifluoromethyl)-2-[4-(trifluo...)
Affinity DataEC50:  4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  1nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28702(2-[2-methyl-4-(2-{4-methyl-2-[4-(trifluoromethyl)p...)
Affinity DataEC50:  4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28703(2-methyl-2-[4-(2-{4-methyl-2-[4-(trifluoromethyl)p...)
Affinity DataEC50:  20nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28704(2-methyl-2-[4-({4-methyl-2-[4-(trifluoromethyl)phe...)
Affinity DataEC50: >1.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
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