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TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292146(US10100057, Example 1 | US9745310, Example 1 | US1...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292147(US10100057, Example 2 | US9745310, Example 2 | US1...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292148(US10100057, Example 3 | US9745310, Example 3 | US1...)
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292149(US10100057, Example 4 | US9745310, Example 4 | US1...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292150(US10100057, Example 5 | US9745310, Example 5 | US1...)
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292151(US10100057, Example 6 | US9745310, Example 6 | US1...)
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292152(US10100057, Example 7 | US9745310, Example 7 | US1...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292153(US10100057, Example 59 | US10100057, Example 8 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292154(US10100057, Example 9 | US9745310, Example 9 | US1...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292155(US10100057, Example 10 | US9745310, Example 10 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292156(US10100057, Example 11 | US9745310, Example 11 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292157(US10100057, Example 12 | US9745310, Example 12 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292158(US10100057, Example 13 | US9745310, Example 13 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292159(US10100057, Example 14 | US9745310, Example 14 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292160(US10100057, Example 15 | US9745310, Example 15 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292161(US10100057, Example 16 | US9745310, Example 16 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292162(US10100057, Example 17 | US9745310, Example 17 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292163(US10100057, Example 18 | US9745310, Example 18 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292164(US10100057, Example 19 | US9745310, Example 19 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292165(US10100057, Example 20 | US9745310, Example 20 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292166(US10100057, Example 21 | US9745310, Example 21 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292167(US10100057, Example 22 | US9745310, Example 22 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292168(US10100057, Example 23 | US9745310, Example 23 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292169(US10100057, Example 24 | US9745310, Example 24 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292170(US10100057, Example 25 | US9745310, Example 25 | U...)
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292171(US10100057, Example 26 | US9745310, Example 26 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292172(US10100057, Example 27 | US9745310, Example 27 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292173(US10100057, Example 28 | US9745310, Example 28 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292174(US10100057, Example 29 | US9745310, Example 29 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292175(US10100057, Example 30 | US9745310, Example 30 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292176(US10100057, Example 31 | US9745310, Example 31 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292177(US10100057, Example 32 | US9745310, Example 32 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292178(US10100057, Example 33 | US9745310, Example 33 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292179(US10100057, Example 34 | US9745310, Example 34 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292180(US10100057, Example 35 | US9745310, Example 35 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292181(US10100057, Example 36 | US9745310, Example 36 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292182(US10100057, Example 37 | US9745310, Example 37 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292183(US10100057, Example 38 | US9745310, Example 38 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292184(US10100057, Example 39 | US9745310, Example 39 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292185(US10100057, Example 40 | US9745310, Example 40 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292186(US10100057, Example 41 | US9745310, Example 41 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292187(US10100057, Example 42 | US9745310, Example 42 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292188(US10100057, Example 43 | US9745310, Example 43 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292189(US10100057, Example 44 | US9745310, Example 44 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292190(US10100057, Example 45 | US9745310, Example 45 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292191(US10100057, Example 46 | US9745310, Example 46 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292192(US10100057, Example 47 | US9745310, Example 47 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292193(US10100057, Example 48 | US9745310, Example 48 | U...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292194(US10100057, Example 49 | US9745310, Example 49 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292195(US10100057, Example 50 | US9745310, Example 50 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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