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TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457887(US10752588, Compound 114a)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457894(US10752588, Compound 6)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457885(US10752588, Compound 79b)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457884(US10752588, Compound 79)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457883(US10752588, Compound 42)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457881(US10752588, Compound 94b)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457880(US10752588, Compound 94a)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457879(US10752588, Compound 95)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457899(US10752588, Compound 125)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457898(US10752588, Compound 69b)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457897(US10752588, Compound 53)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457896(US10752588, Compound 92)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457876(US10752588, Compound 63)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457889(US10752588, Compound 72 | US10752588, Compound 72a)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457891(US10752588, Compound 77a)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457892(US10752588, Compound 66)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457886(US10752588, Compound 114)
Affinity DataKi:  55nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580148(US11498896, Compound 135)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580146(US11498896, Compound 123)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580142(US11498896, Compound 110)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580141(US11498896, Compound 106)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580136(US11498896, Compound 98a)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580132(US11498896, Compound 86)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457901(US10752588, Compound 144a)
Affinity DataKi: <100nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457889(US10752588, Compound 72 | US10752588, Compound 72a)
Affinity DataKi: <100nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457888(US10752588, Compound 105)
Affinity DataKi: <100nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580149(US11498896, Compound 137)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580162(US11498896, Compound 211)
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi: <100nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580160(US11498896, Compound 209)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580161(US11498896, Compound 210)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457877(US10752588, Compound 25)
Affinity DataKi:  550nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457878(US10752588, Compound 35b)
Affinity DataKi:  550nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457882(US10752588, Compound 40)
Affinity DataKi:  550nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM457900(US10752588, Compound 128b)
Affinity DataKi:  550nMAssay Description:radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580125(US11498896, Compound 27)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580130(US11498896, Compound 68)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580131(US11498896, Compound 78)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50518039(CHEMBL4467883 | US11498896, Compound 90)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580134(US11498896, Compound 91)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580135(US11498896, Compound 96)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580137(US11498896, Compound 99)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580140(US11498896, Compound 102a)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580143(US11498896, Compound 112)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580145(US11498896, Compound 122)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580151(US11498896, Compound 144)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM580152(US11498896, Compound 157)
Affinity DataKi:  550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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