Compile Data Set for Download or QSAR
Found 9970 with Last Name = 'liu' and Initial = 's'
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM200((2S)-N-[(2S,3R,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[...)
Affinity DataKi:  0.00400nM ΔG°:  -66.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM198((2S)-N-[(2S,3S,4S,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.0110nM ΔG°:  -63.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM199((2S)-N-[(2S,3R,4S,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.0120nM ΔG°:  -63.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600748(CHEMBL5176737)
Affinity DataKi:  0.0810nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM197((2S)-N-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.112nM ΔG°:  -57.7kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly and Company

LigandPNGBDBM19968((2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  0.170nM ΔG°:  -55.2kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Northeast Louisiana University

Curated by ChEMBL
LigandPNGBDBM50068071(CHEMBL2370908 | SRIF)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly and Company

LigandPNGBDBM19986((2R,6S,7R)-7-(4-hydroxyphenyl)-10-methyl-8-oxatric...)
Affinity DataKi:  0.260nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly and Company

LigandPNGBDBM19987((2R,6S,7R)-7-(4-hydroxyphenyl)-10-(methoxymethyl)-...)
Affinity DataKi:  0.280nM ΔG°:  -54.0kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Northeast Louisiana University

Curated by ChEMBL
LigandPNGBDBM50272772(10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propionyla...)
Affinity DataKi:  0.300nMAssay Description:In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Northeast Louisiana University

Curated by ChEMBL
LigandPNGBDBM50068063((12S,15R,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hyd...)
Affinity DataKi:  0.300nMAssay Description:In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600748(CHEMBL5176737)
Affinity DataKi:  0.302nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly and Company

LigandPNGBDBM19988((2R,6S,7R)-10-(ethoxymethyl)-7-(4-hydroxyphenyl)-8...)
Affinity DataKi:  0.745nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005708(CHEMBL3235459)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50135453((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-3-isopropyl-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50135460((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-4'-fluoro-5-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600757(CHEMBL5208415)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133128(5-{2-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory concentration against Rhizopus chinensis pepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133119(5-{2-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50135462((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3'-fluoro-5-...)
Affinity DataKi:  1nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50129723(7-[2-(2-Fluoro-ethoxy)-3,5-diisopropyl-phenyl]-3-m...)
Affinity DataKi:  1nMAssay Description:Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50129719(7-(3,5-Di-tert-butyl-2-methoxy-phenyl)-3-methyl-oc...)
Affinity DataKi:  1nMAssay Description:Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133119(5-{2-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-p...)
Affinity DataKi:  1nMAssay Description:Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50129717(7-(3,5-Diisopropyl-2-methoxy-phenyl)-3-methyl-octa...)
Affinity DataKi:  1nMAssay Description:Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]-9-cis-RA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005672(CHEMBL3235447)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM170440(US9085531, 40)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM170440(US9085531, 40)
Affinity DataKi:  1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600736(CHEMBL5169483)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005692(CHEMBL3235455)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Northeast Louisiana University

Curated by ChEMBL
LigandPNGBDBM50068071(CHEMBL2370908 | SRIF)
Affinity DataKi:  1.40nMAssay Description:In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM170452(US9085531, 97)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50129720((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005707(CHEMBL3235458)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600758(CHEMBL5174275)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRetinoic acid receptor RXR-beta(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133118(5-{3-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-phen...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600743(CHEMBL5181565)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM493757(US10988455, Example 1(xcv))
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005691(CHEMBL3235454)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50005671(CHEMBL3235446)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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