Compile Data Set for Download or QSAR
Report error Found 5770 with Last Name = 'müller' and Initial = 's'
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537138(CHEMBL4531690)
Affinity DataIC50: 0.0110nMAssay Description:Displacement of fluorescent tracer from N-terminus of human RIPK2 expressed in HEK293T cells after 2 hrs by NanoBRET target engagement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCUGBP Elav-like family member 2(Homo sapiens)TBA
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.0460nMAssay Description:Binding affinity to human CELF2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537138(CHEMBL4531690)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of fluorescent tracer from N-terminus of human GAK expressed in HEK293T cells after 2 hrs by NanoBRET target engagement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.0860nMAssay Description:Binding affinity to human TESK1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.0890nMAssay Description:Binding affinity to human PDGFRB incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSorting nexin-2(Homo sapiens)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human SNX2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human EIF4B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.129nMAssay Description:Binding affinity to human PRKCD incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50274586(CHEMBL4128181)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.132nMAssay Description:Binding affinity to human P4HA1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataEC50:  0.180nMAssay Description:Inhibition of MST2 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.187nMAssay Description:Binding affinity to human NSUN2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataEC50:  0.190nMAssay Description:Inhibition of MST1 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.204nMAssay Description:Binding affinity to human NOP2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50274605(CHEMBL4128266)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetUncharacterized protein FLJ45252(Homo sapiens)TBA
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human FLJ45252 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.214nMAssay Description:Binding affinity to human SLIRP incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.216nMAssay Description:Binding affinity to human CCT5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.224nMAssay Description:Binding affinity to human CLK1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.236nMAssay Description:Binding affinity to human RPS9 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.253nMAssay Description:Binding affinity to human KDELR1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetRRP12-like protein(Homo sapiens)TBA
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.256nMAssay Description:Binding affinity to human RRP12 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.266nMAssay Description:Binding affinity to human TGFBR1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.296nMAssay Description:Binding affinity to human CDK6 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEphrin type-A receptor 3(Human)TBA
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Nano Luc-fused full length C-terminal EPHA3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human BRD7 by BROMOScan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 3(Human)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Nano Luc-fused full length C-terminal EPHA3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetRNA cytidine acetyltransferase(Homo sapiens)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.302nMAssay Description:Binding affinity to human NAT10 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.308nMAssay Description:Binding affinity to human NUMA1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.314nMAssay Description:Binding affinity to human TELO2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.315nMAssay Description:Binding affinity to human PLEKHG3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.317nMAssay Description:Binding affinity to human MYLK incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetWASH complex subunit 5(Homo sapiens)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.337nMAssay Description:Binding affinity to human KIAA0196 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.362nMAssay Description:Binding affinity to human ABCE1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.373nMAssay Description:Binding affinity to human KDM1A incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50274584(CHEMBL4125719)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.411nMAssay Description:Binding affinity to human QTRTD1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCullin-1(Human)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.443nMAssay Description:Binding affinity to human CUL1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.466nMAssay Description:Binding affinity to human LYPLA1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEpithelial cell adhesion molecule(Homo sapiens)TBA
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.472nMAssay Description:Binding affinity to human EPCAM incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.486nMAssay Description:Binding affinity to human PSMD5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetElongation factor 1-gamma(Homo sapiens)TBA
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.491nMAssay Description:Binding affinity to human EEF1G incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.495nMAssay Description:Binding affinity to human NAPRT incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50541792(CHEMBL4635011)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK1(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetLarge subunit GTPase 1 homolog(Homo sapiens)TBA
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.521nMAssay Description:Binding affinity to human LSG1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.531nMAssay Description:Binding affinity to human U2AF1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.546nMAssay Description:Binding affinity to human HSP90AB1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  0.550nMAssay Description:Binding affinity to human CYC1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
Displayed 1 to 50 (of 5770 total ) | Next | Last >>
Jump to: