Compile Data Set for Download or QSAR
Report error Found 759 with Last Name = 'malik' and Initial = 'a'
TargetCasein kinase I(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  150nMAssay Description:Binding affinity to CK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human aryl hydrocarbon receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  60nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase I(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  150nMAssay Description:Binding affinity to CK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase I(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to CK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase I(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to CK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  60nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  60nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human aryl hydrocarbon receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataKd:  50nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530637(CHEMBL4591417)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  60nMAssay Description:Binding affinity to CDPK4 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530659(CHEMBL4461850)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr in presence of ATP-competitive kinase inhibitor by kino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Mouse)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50088378(CHEBI:68478 | Afinitor | Afinitor Disperz | Everol...)
Affinity DataIC50: 0.00500nMAssay Description:Inhibition of mTOR in Tsc1 knockout mouse neurons assessed as reduction in phosphorylated S6 level incubated for 4 hrs by Hoechst staining based immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50360084(CHEMBL1928725)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360090(CHEMBL1928555)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530642(CHEMBL4531058)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50360085(CHEMBL1928726)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360024(CHEMBL1928541)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360024(CHEMBL1928541)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530662(CHEMBL4459320)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530662(CHEMBL4459320)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50360063(CHEMBL1928561)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360081(CHEMBL1928722)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530639(CHEMBL4461276)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530639(CHEMBL4461276)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530649(CHEMBL4451783)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530653(CHEMBL4469667)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530656(CHEMBL4449947)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530649(CHEMBL4451783)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530663(CHEMBL4532321)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530663(CHEMBL4532321)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530656(CHEMBL4449947)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530653(CHEMBL4469667)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50360082(CHEMBL1928723)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant PI3K p110alpha using L-alpha-phosphatidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50467123(CHEMBL4288103)
Affinity DataIC50: 2nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
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