Compile Data Set for Download or QSAR
Report error Found 1014 with Last Name = 'marathe' and Initial = 'p'
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20670(phenyl N-(4-methyl-3-{[5-methyl-6-(propylcarbamoyl...)
Affinity DataAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20647(ethyl 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amin...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20646(ethyl 5-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphe...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20642(methyl 4-{[5-(ethylcarbamoyl)-2-methylphenyl]amino...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of lck inaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20655(N-benzyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]a...)
Affinity DataIC50: 0.400nM EC50:  9.60nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Yes(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of yes kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20650(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)
Affinity DataIC50: 0.900nM EC50:  30nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20645(ethyl 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amin...)
Affinity DataIC50: 0.900nM EC50:  37nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Bcr-Abl kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20640(methyl 4-{[5-(methoxycarbamoyl)-2-methylphenyl]ami...)
Affinity DataIC50: 1.10nM EC50:  160nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20656(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)
Affinity DataIC50: 1.20nM EC50:  2.40nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20666(propan-2-yl N-(4-{[5-(methoxycarbamoyl)-2-methylph...)
Affinity DataIC50: 1.20nM EC50:  110nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24457(2-[(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}p...)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50236473((R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbam...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20665(ethyl N-(4-{[5-(methoxycarbamoyl)-2-methylphenyl]a...)
Affinity DataIC50: 1.5nM EC50:  26nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM50235904(N-(R)-sec-butyl-6-(4-(2-fluorophenyl)-1H-imidazol-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24458(2-[(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}p...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318222(4-((5S,9R)-7-(5-(1H-Tetrazol-5-yl)pyridin-2-yl)-3-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318219(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24440(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24441(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM50236476(N-(5-(ethylcarbamoyl)-2-methylphenyl)-2-(propylami...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50533641(CHEMBL4460221)
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged full length human recombinant BTK expressed in baculovirus using fluoresceinated peptide substrate after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50533649(CHEMBL4467132)
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged full length human recombinant BTK expressed in baculovirus using fluoresceinated peptide substrate after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50533652(CHEMBL4543505)
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged full length human recombinant BTK expressed in baculovirus using fluoresceinated peptide substrate after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM50272049(1-(4-(2-amino-3-ethynylpyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Met kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM50271981(1-(3-fluoro-4-(3-(pyridin-3-yl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Met kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM50272012(1-(3-fluoro-4-(2-(pyridin-3-yl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Met kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5666(N-(2,6-Difluorophenyl)-N-[5-[[[5-tert-butyl-2-oxaz...)
Affinity DataIC50: 2nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20657(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)
Affinity DataIC50: 2.20nM EC50:  10nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20653(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-N-(...)
Affinity DataIC50: 2.20nM EC50:  140nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20657(4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-m...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24454(1-(3-fluoro-4-methoxyphenyl)-N-(3-fluoro-4-{1H-pyr...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM50236483((S)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbam...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318220(6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM50235905(N-(S)-sec-butyl-6-(4-(2-fluorophenyl)-1H-imidazol-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24449(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 2.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50194715(CHEMBL3918580)
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged full length human recombinant BTK expressed in baculovirus using fluoresceinated peptide substrate after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM50348884(CHEMBL1807448)
Affinity DataIC50: 3nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5924(N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfan...)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2005
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM50272013(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Met kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50199036(4-[(5S,9R)-3-(3,5-dichloro-phenyl)-1-methyl-2,4-di...)
Affinity DataIC50: 3nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20652(N-[(2S)-butan-2-yl]-4-{[5-(methoxycarbamoyl)-2-met...)
Affinity DataIC50: 3nM EC50: <2nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5668(N-[5-[[[5-tert-Butyl-2-oxazolyl]methyl]thio]-2-thi...)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50533650(CHEMBL4550390)
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged full length human recombinant BTK expressed in baculovirus using fluoresceinated peptide substrate after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5667(3-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfan...)
Affinity DataIC50: 3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5668(N-[5-[[[5-tert-Butyl-2-oxazolyl]methyl]thio]-2-thi...)
Affinity DataIC50: 3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5708(N-(5-{[(2-tert-butyl-1,3-oxazol-5-yl)methyl]sulfan...)
Affinity DataIC50: 3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed
Displayed 1 to 50 (of 1014 total ) | Next | Last >>
Jump to: