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TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546842(CHEMBL4761419)
Affinity DataKi:  0.450nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546817(CHEMBL4760409)
Affinity DataKi:  0.5nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546819(CHEMBL4793824)
Affinity DataKi:  0.600nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165586(CHEMBL3798559)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102978(US8546435, 6)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546815(CHEMBL4744051)
Affinity DataKi:  1nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517283(CHEMBL425281)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517281(CHEMBL4517399)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546824(CHEMBL4753794)
Affinity DataEC50:  1.40nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293 cells assessed as inhibition of ghrelin-induced IP1 response measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546828(CHEMBL4753046)
Affinity DataKi:  1.40nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetType-1 angiotensin II receptor A(Rat)
Laboratoires Fournier

Curated by ChEMBL
LigandPNGBDBM50082568(2-({3-[4-(2-Azido-benzenesulfonylaminocarbonyl)-be...)
Affinity DataKi:  1.5nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517283(CHEMBL425281)
Affinity DataEC50:  1.5nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102976(US8546435, 4)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165592(CHEMBL3799776)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102979(US8546435, 7)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102975(US8546435, 3)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165592(CHEMBL3799776)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165587(CHEMBL3800298)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102978(US8546435, 6)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546818(CHEMBL4745116)
Affinity DataKi:  2.40nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165582(CHEMBL3797225)
Affinity DataKi:  2.5nM ΔG°:  -49.1kJ/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataEC50:  2.5nMAssay Description:Antagonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in ghrelin-induced inositol phosphate production at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
Laboratoires Fournier

Curated by ChEMBL
LigandPNGBDBM50082567(2-{2-butyl-1-[4-(2-chlorophenylsulfonamidocarbonyl...)
Affinity DataKi:  2.5nMAssay Description:The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517280(CHEMBL4463042)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102977(US8546435, 5)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546816(CHEMBL4777792)
Affinity DataKi:  3nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165589(CHEMBL3798095)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165590(CHEMBL3799225)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546824(CHEMBL4753794)
Affinity DataKi:  3nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165588(CHEMBL3800422)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102975(US8546435, 3)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102979(US8546435, 7)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517278(CHEMBL4475293)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517279(CHEMBL4456830)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546831(CHEMBL4781141)
Affinity DataKi:  3.40nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546823(CHEMBL4791255)
Affinity DataEC50:  3.60nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293 cells assessed as inhibition of ghrelin-induced IP1 response measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50517282(CHEMBL4556887)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50396915(CHEMBL2170781)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-His9 ghrelin from SNAP-tagged human GHSR expressed in HEK293T cells after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165582(CHEMBL3797225)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165591(CHEMBL3798155)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546843(CHEMBL4780843)
Affinity DataKi:  4nMAssay Description:Displacement of red-ghrelin from SNAP-tagged human GHSR expressed in HEK293 cells incubated for 3 hrs at 4 degC or for 1 hr at room temperature by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165594(CHEMBL3797531)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50144624((5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pipera...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165592(CHEMBL3799776)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165591(CHEMBL3798155)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165590(CHEMBL3799225)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM102976(US8546435, 4)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50165587(CHEMBL3800298)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50396915(CHEMBL2170781)
Affinity DataEC50:  5.5nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293T cells assessed as reduction in inositol phosphate production after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Univ Montpellier

Curated by ChEMBL
LigandPNGBDBM50546827(CHEMBL4797064)
Affinity DataEC50:  6nMAssay Description:Inverse agonist activity at SNAP-tagged human GHSR expressed in HEK293 cells assessed as inhibition of ghrelin-induced IP1 response measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
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