Report error Found 2525 with Last Name = 'mckenna' and Initial = 'r'
Affinity DataKd: 240nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.62E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 70nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 605nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.75E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by isothermal calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+8nMAssay Description:Binding affinity to human CA9More data for this Ligand-Target Pair
Affinity DataKd: 4.50E+8nMAssay Description:Binding affinity to human CA2More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human CAH9 catalytic domain expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl ace...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human full length CAH2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human full length CAH2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human CAH9 catalytic domain expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl ace...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.85E+5nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [482-580,I502K,I528M,T553A](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.0190nM ΔG°: -63.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.0210nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.0400nM ΔG°: -61.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.0500nM ΔG°: -61.2kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.170nM ΔG°: -58.0kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.190nM ΔG°: -57.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,V583F](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [482-580,I502K,I528M,T553A](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [482-580,I502K,I528M,T553A](Human immunodeficiency virus type 1)
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataKi: 0.240nM ΔG°: -57.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human CAH7 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
