Compile Data Set for Download or QSAR
Report error Found 3594 with Last Name = 'park' and Initial = 'ch'
LigandPNGBDBM24945(20-hydroxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24946(3-(2-hydroxyethyl)-3,13-diazahexacyclo[14.8.0.0^{2...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24950(20-hydroxy-3-(2-hydroxyethyl)-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24951(20-(cyclopropylmethoxy)-3-(2-hydroxyethyl)-3,13-di...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24953(20-(cyclohexyloxy)-3-(2-hydroxyethyl)-3,13-diazahe...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24954(3-(2-hydroxyethyl)-20-(pyridin-2-ylmethoxy)-3,13-d...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24955(3-(2-hydroxyethyl)-20-(2-methoxyethoxy)-3,13-diaza...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24956(20-[2-(benzyloxy)ethoxy]-3-(2-hydroxyethyl)-3,13-d...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24957(20-(2-hydroxyethoxy)-3-(2-hydroxyethyl)-3,13-diaza...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24958(2-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24959(4-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24945(20-hydroxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24950(20-hydroxy-3-(2-hydroxyethyl)-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24951(20-(cyclopropylmethoxy)-3-(2-hydroxyethyl)-3,13-di...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24952(20-(cyclopentyloxy)-3-(2-hydroxyethyl)-3,13-diazah...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24953(20-(cyclohexyloxy)-3-(2-hydroxyethyl)-3,13-diazahe...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24954(3-(2-hydroxyethyl)-20-(pyridin-2-ylmethoxy)-3,13-d...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24955(3-(2-hydroxyethyl)-20-(2-methoxyethoxy)-3,13-diaza...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24956(20-[2-(benzyloxy)ethoxy]-3-(2-hydroxyethyl)-3,13-d...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24957(20-(2-hydroxyethoxy)-3-(2-hydroxyethyl)-3,13-diaza...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24958(2-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24959(4-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DataAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Mouse)
Abbvie

US Patent
LigandPNGBDBM178731(US9125913, 300)
Affinity DataAssay Description:The inhibition constant (Ki) is the dissociation constant of an enzyme-inhibitor complex or a protein/small molecule complex, wherein the small molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220473(US9296741, 62)
Affinity DataEC50:  19nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220422(US9296741, 11)
Affinity DataEC50:  67nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220474(US9296741, 63)
Affinity DataEC50:  120nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220468(US9296741, 57)
Affinity DataEC50:  18nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220440(US9296741, 29)
Affinity DataEC50:  90nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 7(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BRD7 (L125 to R254 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 8(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BRD8 (1) (S700 to F854 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BAZ2A (M1792 to L1905 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain-2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human WDR9(2) (A1310 to E1430 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241734(CHEMBL4082851)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241735(CHEMBL4100828)
Affinity DataEC50:  8.50E+3nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220415(US9296741, 4)
Affinity DataEC50:  11nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220432(US9296741, 21)
Affinity DataEC50:  8.10nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220416(US9296741, 5)
Affinity DataEC50:  22nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220434(US9296741, 23)
Affinity DataEC50:  88nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220417(US9296741, 6)
Affinity DataEC50:  26nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220430(US9296741, 19)
Affinity DataEC50:  71nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220496(US9296741, 85)
Affinity DataEC50:  50nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220506(US9296741, 95)
Affinity DataEC50:  39nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220501(US9296741, 90)
Affinity DataEC50:  48nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241743(CHEMBL4059602)
Affinity DataEC50:  65nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50241744(CHEMBL4060619)
Affinity DataEC50:  76nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220438(US9296741, 27)
Affinity DataEC50:  21nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataEC50:  20nMAssay Description:Inhibition of BRD4 in human H1299 cells assessed as decrease in HPV LCR-E2-EP400-mediated transcriptional repression after 24 hrs by Bright-Glo lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
Displayed 1 to 50 (of 3594 total ) | Next | Last >>
Jump to: