Compile Data Set for Download or QSAR
Report error Found 14 with Last Name = 'patel' and Initial = 'mp'
TargetCytochrome P450 3A4(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of CYP3A4 using in human liver microsomes using testosterone as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 18nMAssay Description:Inhibition of CYP3A4 using in human liver microsomes using midazolam as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2C9(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50090677(CHEMBL1109 | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 205nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataIC50: 6.29E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-2-phenylcyclopropanamine | cid_2723716 | (...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-Mephentoin as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of CYP3A4 using in human liver microsomes using testosterone as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-Mephentoin as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 5.86E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 8.19E+4nMAssay Description:Inhibition of CYP3A4 using in human liver microsomes using midazolam as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50235297(CHEMBL4101807)
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed