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TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97707(US8476255, 95)
Affinity DataIC50: 10nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97708(US8476255, 96)
Affinity DataIC50: 10nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97695(US8476255, 55)
Affinity DataIC50: 20nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97698(US8476255, 59)
Affinity DataIC50: 30nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97703(US8476255, 89)
Affinity DataIC50: 30nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97685(US8476255, 28)
Affinity DataIC50: 36nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97694(US8476255, 53)
Affinity DataIC50: 40nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97697(US8476255, 58)
Affinity DataIC50: 40nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97704(US8476255, 90)
Affinity DataIC50: 40nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97706(US8476255, 94)
Affinity DataIC50: 40nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97680(US8476255, 19)
Affinity DataIC50: 42nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97700(US8476255, 77)
Affinity DataIC50: 50nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97684(US8476255, 27)
Affinity DataIC50: 50nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97688(US8476255, 32)
Affinity DataIC50: 52nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97687(US8476255, 31)
Affinity DataIC50: 54nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97686(US8476255, 29)
Affinity DataIC50: 57nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97693(US8476255, 52)
Affinity DataIC50: 60nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97699(BOC-LYS(AC)-AMC | US8476255, 76)
Affinity DataIC50: 60nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97701(US8476255, 84)
Affinity DataIC50: 60nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97683(US8476255, 24)
Affinity DataIC50: 62nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97696(US8476255, 57)
Affinity DataIC50: 70nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97709(US8476255, 101)
Affinity DataIC50: 70nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97681(US8476255, 20)
Affinity DataIC50: 150nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97705(US8476255, 92)
Affinity DataIC50: 240nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97692(US8476255, 49)
Affinity DataIC50: 330nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97702(US8476255, 85)
Affinity DataIC50: 380nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50237619(CHEBI:28545 | Valino | Valinomycin)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97682(US8476255, 22)
Affinity DataIC50: 3.20E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50001285(3-(((3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)(...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97679(US8476255, 15)
Affinity DataIC50: 3.80E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50378137(Ketek | TELITHROMYCIN)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97688(US8476255, 32)
Affinity DataIC50: 4.80E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50213021(CHEBI:63621 | Fortovase | Invirase | Ro-31-8959 | ...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97691(US8476255, 37)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50088494(CI-991 | Rezulin | Prelay | CHEMBL3542292 | Gr9213...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069447(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97689(US8476255, 33)
Affinity DataIC50: 7.80E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97687(US8476255, 31)
Affinity DataIC50: 7.90E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50017712(Apoplon | 3,4,5-trimethoxybenzoyl methyl reserpate...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97680(US8476255, 19)
Affinity DataIC50: 8.60E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 1(Mouse)
Orchid Chemicals & Pharmaceuticals

US Patent
LigandPNGBDBM97685(US8476255, 28)
Affinity DataIC50: 9.50E+3nMT: 2°CAssay Description:Assay was done in 96-well black microplate and total volume of the assay was 100 pt. Mouse liver enzyme (10 mg/ml) was diluted 1:6 with HDAC buffer. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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