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TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620671(CHEMBL5428441)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620673(CHEMBL5416318)
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620672(CHEMBL5421145)
Affinity DataIC50: 12nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620670(CHEMBL5396894)
Affinity DataIC50: 69nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564233(CHEMBL4792854)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564234(CHEMBL4783905)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564233(CHEMBL4792854)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564237(CHEMBL4793095)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564238(CHEMBL4791125)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564237(CHEMBL4793095)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564239(CHEMBL4779198)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564236(CHEMBL4782789)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564235(CHEMBL4793871)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBeta-galactosidase(Aspergillus niger)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403936(CHEMBL2114148)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitor concentration against Beta-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50321922((3S,4S,5R,6S)-3-(p-Phenylbenzoylaminomethyl)-6-met...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of bovine kidney alpha L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50468278(CHEMBL4294263)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycopyranoside as substrate preincubated for 5 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456589(CHEMBL4211283)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-galactosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403936(CHEMBL2114148)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitor concentration of compound against beta-Galactosidase from Jack beansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-galactosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403936(CHEMBL2114148)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitor concentration against Beta-galactosidase from Aspergillus oryzaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564249(CHEMBL4789325)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456587(CHEMBL4209809)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456590(CHEMBL4206239)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564236(CHEMBL4782789)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456586(CHEMBL4205735)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456586(CHEMBL4205735)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456591(CHEMBL4214151)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564235(CHEMBL4793871)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucoamylase 1(Mucormycosis agent)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity towards Alpha-glucosidase from Rhizopus mold (amyloglucosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456590(CHEMBL4206239)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-galactosidase(Aspergillus niger)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403937(CHEMBL2114149)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitor concentration against Beta-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-galactosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403937(CHEMBL2114149)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitor concentration against Beta-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564251(CHEMBL4781544)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50321921((3S,4S,5R,6S)-3-Hydroxymethyl-6-methylhexahydropyr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of bovine kidney alpha L-fucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucoamylase(Aspergillus niger)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity towards Alpha-glucosidase from Aspergillus niger (amyloglucosidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564240(CHEMBL4786169)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564241(CHEMBL4214414)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403938(CHEMBL2114150)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitor concentration against alpha-L-Fucosidase from Bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104397(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104396(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456586(CHEMBL4205735)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50403937(CHEMBL2114149)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibitor concentration against Beta-galactosidase from Bovine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50104386(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against alpha-L-Fucosidase of bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Targetalpha-1,2-Mannosidase(Soybean)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104307(2-(Benzylamino-methyl)-pyrrolidine-3,4-diol | CHEM...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity towards Alpha-mannosidase from Jack beanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403937(CHEMBL2114149)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitor concentration against Beta-galactosidase from Aspergillus oryzae was tested at a dose of 1 mMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-glucosidase(Cherry)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104296(2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from AlmondMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50403938(CHEMBL2114150)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitor concentration against alpha-L-Fucosidase from Human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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