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TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577476(CHEMBL4852406)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50561036(CHEMBL4778978)
Affinity DataEC50:  6.90E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566337(CHEMBL4862596)
Affinity DataEC50:  9.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566349(CHEMBL4854745)
Affinity DataEC50:  0.740nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577474(CHEMBL4876150)
Affinity DataEC50:  6.30E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566334(CHEMBL4872775)
Affinity DataEC50:  21nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566351(CHEMBL4847518)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566350(CHEMBL4873949)
Affinity DataEC50:  0.970nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566328(CHEMBL4869259)
Affinity DataEC50:  4nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566345(CHEMBL4846178)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566342(CHEMBL4873952)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566352(CHEMBL4861625)
Affinity DataEC50:  0.840nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50566335(CHEMBL4864483)
Affinity DataEC50:  32nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566326(CHEMBL4860893)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566321(CHEMBL4867267)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577480(CHEMBL4862982)
Affinity DataEC50:  2.80E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50561035(CHEMBL4763578)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566341(CHEMBL4849342)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577475(CHEMBL4855923)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566325(CHEMBL4846860)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566346(CHEMBL4868904)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566327(CHEMBL4868831)
Affinity DataEC50:  4.70nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577477(CHEMBL4868283)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566330(CHEMBL4874774)
Affinity DataEC50: <0.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566323(CHEMBL4860414)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577473(CHEMBL4871410)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566322(CHEMBL4853705)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566324(CHEMBL4851358)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566329(CHEMBL4868773)
Affinity DataEC50:  38nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566331(CHEMBL4874354)
Affinity DataEC50:  2.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577479(CHEMBL4862990)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566333(CHEMBL4862310)
Affinity DataEC50: >10nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566344(CHEMBL4850190)
Affinity DataEC50:  2.80nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566353(CHEMBL4862485)
Affinity DataEC50:  11nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566339(CHEMBL4854567)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566343(CHEMBL4878171)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577458(CHEMBL4858437)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577478(CHEMBL4872801)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50566338(CHEMBL4853843)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566332(CHEMBL4848739)
Affinity DataEC50:  14nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566336(CHEMBL4849067)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566340(CHEMBL4853251)
Affinity DataEC50:  9.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566348(CHEMBL4852843)
Affinity DataEC50:  0.890nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
LigandPNGBDBM50566347(CHEMBL4867460)
Affinity DataEC50:  0.870nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50561042(CHEMBL4748950)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50579614(CHEMBL4871970)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ARG1 (unknown origin) assessed as reduction in thio-ornithine production using thioarginine as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50577469(CHEMBL4850213)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50579610(CHEMBL4873520)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ARG1 (unknown origin) assessed as reduction in thio-ornithine production using thioarginine as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50561035(CHEMBL4763578)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Quantitative Biosciences

Curated by ChEMBL
LigandPNGBDBM50579616(CHEMBL4845730)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of ARG1 (unknown origin) assessed as reduction in thio-ornithine production using thioarginine as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
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