Report error Found 118 with Last Name = 'schürer' and Initial = 'sc'
Affinity DataEC50: 2.75E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of helicase activity of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using Cy3-labele...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of helicase activity of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using Cy3-labele...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.66E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110L mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110M mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110E mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A T158A mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A T158V mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R311K mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R311E mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.21E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Human)
University of Michigan Medical School
Curated by ChEMBL
University of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.41E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.48E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
