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TargetTranscriptional enhancer factor TEF-3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50535722(CHEMBL4468725)
Affinity DataKd:  25nMAssay Description:Binding affinity to Avi-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21 (DE3) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM695278(US12083101, Example 27a)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695279(US12083101, Example 27b)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695310(US12083101, Example 55b | US12083101, Example 55a)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695340(US12083101, Example 71b)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM50626283(US12083101, Example 106 | CHEMBL5400107)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM695385(US12083101, Example 110)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695387(US12083101, Example 112)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695393(US12083101, Example 116a)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695394(US12083101, Example 116b)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695395(US12083101, Example 117a)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695396(US12083101, Example 117b)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695397(US12083101, Example 118)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695431(US12083101, Example 147)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695437(US12083101, Example 153 | 2-((2S,4S)-5-Chloro-6-fl...)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695454(US12083101, Example 170)
Affinity DataIC50: 1nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM706074(US20240382600, Example 3)
Ligand Info
In DepthDetails

LigandPNGBDBM706076(US20240382600, Example 5)
Ligand Info
In DepthDetails

LigandPNGBDBM706078(US20240382600, Example 7)
Ligand Info
In DepthDetails

LigandPNGBDBM706082(US20240382600, Example 11)
Ligand Info
In DepthDetails

LigandPNGBDBM706086(US20240382600, Example 15)
Ligand Info
In DepthDetails

LigandPNGBDBM706088(US20240382600, Example 17)
Ligand Info
In DepthDetails

LigandPNGBDBM706093(US20240382600, Example 22)
Ligand Info
In DepthDetails

LigandPNGBDBM706094(US20240382600, Example 23)
Ligand Info
In DepthDetails

LigandPNGBDBM706075(US20240382600, Example 4)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706080(US20240382600, Example 9)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706087(US20240382600, Example 16)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706073(US20240382600, Example 2)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706085(US20240382600, Example 14)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706091(US20240382600, Example 20)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM695263(US12083101, Example 12)
Affinity DataIC50: 1.5nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM706077(US20240382600, Example 6)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706079(US20240382600, Example 8)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706083(US20240382600, Example 12)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706092(US20240382600, Example 21)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706084(US20240382600, Example 13)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706102(US20240382600, Example 31)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706069(US20240382600, Example C-I-k)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM706072(US20240382600, Example 1)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails

LigandPNGBDBM695291(US12083101, Example 37)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695292(US12083101, Example 38)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695302(US12083101, Example 48)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695310(US12083101, Example 55b | US12083101, Example 55a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695312(US12083101, Example 56b | US12083101, Example 56a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695326(US12083101, Example 64a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695330(US12083101, Example 66a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695331(US12083101, Example 66b)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695332(US12083101, Example 67a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695339(US12083101, Example 71a)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

LigandPNGBDBM695341(US12083101, Example 72)
Affinity DataIC50: 2nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

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