Compile Data Set for Download or QSAR
Report error Found 619 with Last Name = 'seal' and Initial = 'jt'
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM85389(CAS_52906-92-0 | Motilin)
Affinity DataEC50:  0.0398nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475465(CHEMBL196410)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475462(CHEMBL371375)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50174269(1-Benzenesulfonyl-4-piperazin-1-yl-1H-indole | 1-(...)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475480(CHEMBL193629)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475467(CHEMBL425015)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475475(CHEMBL372513)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475477(CHEMBL372929)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044607(CHEMBL372537)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475463(CHEMBL194915)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475473(CHEMBL194039)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475470(CHEMBL370209)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475479(CHEMBL371176)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28583(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human partial length BRD4 BD 2 (K333 to E460 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475464(CHEMBL197574)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475466(CHEMBL193665)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475471(CHEMBL371876)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412537(CHEMBL465917)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  2nMAssay Description:Binding affinity to human partial length BRDT BD 2 (K250 to E382 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044623(CHEMBL193400)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475481(CHEMBL197297)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412526(CHEMBL518618)
Affinity DataEC50:  2.51nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412523(CHEMBL465271)
Affinity DataEC50:  3.16nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475478(CHEMBL196644)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412539(CHEMBL518229)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292985(3-((1-[(4-([(3S)-3-Methyl-1-piperazinyl]methyl)phe...)
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475482(CHEMBL193379)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  5nMAssay Description:Binding affinity to human partial length BRD3 BD 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50603097(CHEMBL5195288)
Affinity DataKd:  5nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254970([4'-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-bi...)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412541(CHEMBL465095)
Affinity DataEC50:  5.01nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475472(CHEMBL372287)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50603097(CHEMBL5195288)
Affinity DataKd:  6.30nMAssay Description:Binding affinity to BRD3 BD2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412531(CHEMBL463881)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50603097(CHEMBL5195288)
Affinity DataKd:  7.90nMAssay Description:Binding affinity to BRD2 BD2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475474(CHEMBL426640)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50475476(CHEMBL196103)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044623(CHEMBL193400)
Affinity DataKi:  7.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 receptor of human caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254931(4'-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-bip...)
Affinity DataEC50:  7.94nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50263384(6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazo...)
Affinity DataIC50: 9nMpH: 5.3Assay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of pH 5.3 acid-induced calcium influx by whole cell patch clamp a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50255062({3-[4-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566686(CHEMBL4873182)
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254893(2-Benzenesulfonyl-N-[4'-((3R,5S)-3,5-dimethyl-pipe...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254968([4'-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-bi...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD3 BD2/BD1 Y73A mutant (1 to 435 residues) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254851(3-cyclohexyl-1-((4'-(((3S,5R)-3,5-dimethylpiperazi...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  10nMAssay Description:Binding affinity to human partial length BRD2 BD 2 (E348 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292981(N-(4-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperaz...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 619 total ) | Next | Last >>
Jump to: