Compile Data Set for Download or QSAR
Report error Found 4147 with Last Name = 'shah' and Initial = 's'
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50498590(CHEMBL3609637)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10 | ...)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10 | ...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of human Cav1.2 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)
Affinity DataEC50: >1.10E+4nMAssay Description:Inhibition of human Kv1.5 by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563447(CHEMBL4782568)
Affinity DataEC50:  1.41E+3nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563448(CHEMBL4744049)
Affinity DataEC50:  157nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563449(CHEMBL4755177)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563450(CHEMBL4741006)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563451(CHEMBL4779985)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563452(CHEMBL4748865)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563453(CHEMBL4777445)
Affinity DataEC50:  745nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563454(CHEMBL4760659)
Affinity DataEC50:  805nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563455(CHEMBL4751616)
Affinity DataEC50:  107nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563456(CHEMBL4778466)
Affinity DataEC50:  1.87E+3nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563457(CHEMBL4796294)
Affinity DataEC50:  819nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563458(CHEMBL4784457)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563459(CHEMBL4790521)
Affinity DataEC50:  125nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563460(CHEMBL4790469)
Affinity DataEC50:  720nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563461(CHEMBL4743968)
Affinity DataEC50:  106nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50563462(CHEMBL4789532)
Affinity DataEC50:  153nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50244791((2-Fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopr...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.01E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  8.97E+3nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.22E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  6.62E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  6.08E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  2.19E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetFree fatty acid receptor 1(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50606916(CHEMBL5219102)
Affinity DataEC50:  6.46E+3nMAssay Description:Agonist activity at GPR40 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetFree fatty acid receptor 1(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50606917(CHEMBL5219055)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at GPR40 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetFree fatty acid receptor 1(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50606916(CHEMBL5219102)
Affinity DataEC50:  776nMAssay Description:Positive allosteric modulation of GPR40 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261701(2-Methyl-c-5-[4-(5-methyl-2-phenyloxazol-4-ylmetho...)
Affinity DataEC50:  1.09nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261880(c-5-[4-{2-(2-tert-Butyl-5-methyloxazol-4-yl)ethoxy...)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261879(2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261878(2-Methyl-c-5-{4-[5-methyl-2-(5-methylthiophen-2-yl...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261703(2-Methyl-c-5-{4-[2-(5-methyl-2-(4-methylphenyl)oxa...)
Affinity DataEC50:  0.0890nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261702(2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...)
Affinity DataEC50:  0.272nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50256109((2s,5s)-2-methyl-5-(4-((5-methyl-2-p-tolyloxazol-4...)
Affinity DataEC50:  0.0720nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261880(c-5-[4-{2-(2-tert-Butyl-5-methyloxazol-4-yl)ethoxy...)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261879(2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...)
Affinity DataEC50:  239nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261878(2-Methyl-c-5-{4-[5-methyl-2-(5-methylthiophen-2-yl...)
Affinity DataEC50:  19.8nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261703(2-Methyl-c-5-{4-[2-(5-methyl-2-(4-methylphenyl)oxa...)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261702(2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50256109((2s,5s)-2-methyl-5-(4-((5-methyl-2-p-tolyloxazol-4...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261701(2-Methyl-c-5-[4-(5-methyl-2-phenyloxazol-4-ylmetho...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 4147 total ) | Next | Last >>
Jump to: