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TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4690((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00000600nM ΔG°:  -82.5kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4689((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0000130nM ΔG°:  -80.6kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4685([3H]GW0385 | CHEMBL206031 | (3R,3aS,6aR)-hexahydro...)
Affinity DataKi:  0.0000150nM ΔG°:  -80.2kJ/molepH: 5.5 T: 2°CAssay Description:The assay method employed kinetic determinations of values for k1 and k-1, from which value of inhibition constant (Ki ) was determined (k-1/k1). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4688((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000165nM ΔG°:  -74.2kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4689((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000220nM ΔG°:  -73.5kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4687((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000240nM ΔG°:  -73.2kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4690((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.000420nM ΔG°:  -71.8kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4685([3H]GW0385 | CHEMBL206031 | (3R,3aS,6aR)-hexahydro...)
Affinity DataKi:  0.000750nM ΔG°:  -70.4kJ/molepH: 5.5 T: 2°CAssay Description:The assay method employed kinetic determinations of values for k1 and k-1, from which value of inhibition constant (Ki ) was determined (k-1/k1). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
LigandPNGBDBM4688((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00120nM ΔG°:  -69.2kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
LigandPNGBDBM4690((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00170nM ΔG°:  -68.3kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,I539V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4685([3H]GW0385 | CHEMBL206031 | (3R,3aS,6aR)-hexahydro...)
Affinity DataKi:  0.00200nM ΔG°:  -67.9kJ/molepH: 5.5 T: 2°CAssay Description:The assay method employed kinetic determinations of values for k1 and k-1, from which value of inhibition constant (Ki ) was determined (k-1/k1). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
LigandPNGBDBM4689((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00240nM ΔG°:  -67.4kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,I539V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4690((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00260nM ΔG°:  -67.2kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
LigandPNGBDBM4685([3H]GW0385 | CHEMBL206031 | (3R,3aS,6aR)-hexahydro...)
Affinity DataKi:  0.00340nM ΔG°:  -66.6kJ/molepH: 5.5 T: 2°CAssay Description:The assay method employed kinetic determinations of values for k1 and k-1, from which value of inhibition constant (Ki ) was determined (k-1/k1). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,I539V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4689((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00390nM ΔG°:  -66.2kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4688((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00430nM ΔG°:  -66.0kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,I539V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4688((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.00460nM ΔG°:  -65.8kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,M535I,L552P,A560V,V571F,I573V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4687((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0250nM ΔG°:  -61.5kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587,I539V](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM4687((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0270nM ΔG°:  -61.3kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
LigandPNGBDBM4687((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0544nM ΔG°:  -59.6kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM577(VX-478 | 141W94 | APV | BDBM50215393 | CHEMBL116 |...)
Affinity DataKi:  0.0570nM ΔG°:  -59.5kJ/molepH: 5.5 T: 2°CAssay Description:Enzymatic activity was determined with fluorogenic substrate in the presence and absence of inhibitor. The fluorescence increase due to hydrolysis of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2005
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50005463(1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-phen...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of cholecystokinin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691452(US20240279201, Compound YA6139)
Affinity DataIC50: 0.110nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691451(US20240279201, Compound YA6138)
Affinity DataIC50: 0.150nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305990(N-((1-(4-chloro-2-(2-fluorophenylsulfonyl)phenylsu...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300149((R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(6-(difluor...)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300145((S)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(6...)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293912((R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293974((R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(4-methoxy-...)
Affinity DataIC50: 0.270nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300136((R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(6-methoxy-...)
Affinity DataIC50: 0.280nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293964((S)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4...)
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50389480(CHEMBL2063040)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446659(CHEMBL3116468)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300142((R)-5-Chloro-1-(1-cyclopropylethyl)-3-[6-(difluoro...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Tufts University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50389480(CHEMBL2063040)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50453675(CHEMBL2113400)
Affinity DataKi:  0.330nMAssay Description:Binding affinity against adenosine A3 receptor from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305989(N-((1-(4-chloro-2-(2-fluorophenylsulfonyl)phenylsu...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of full length BTK C481S mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM499812((2-chloro-4-phenoxyphenyl)(4- (((3S,6R)-6-(hydroxy...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691520(US20240279201, Compound YA4155)
Affinity DataIC50: 0.400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691539(US20240279201, Compound YA4025)
Affinity DataIC50: 0.400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446651(CHEMBL3116476)
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293941((R)-5-Chloro-1-(1-cyclopropylethyl)-3-(4-methoxy-2...)
Affinity DataIC50: 0.420nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691495(US20240279201, Compound YA4029)
Affinity DataIC50: 0.460nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691495(US20240279201, Compound YA4029)
Affinity DataIC50: 0.460nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300144((R)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-[6...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
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