Compile Data Set for Download or QSAR
Report error Found 1311 with Last Name = 'silva' and Initial = 'v'
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267262(CHEMBL501253)
Affinity DataIC50: 0.0800nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50587754(CHEMBL5197518)
Affinity DataIC50: 0.0920nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267261(CHEMBL525994)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422313(CHEMBL2310891)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422316(CHEMBL2310888)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50610559(CHEMBL5286535)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM759620(US20250236608, Example 212)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50587754(CHEMBL5197518)
Affinity DataIC50: 0.211nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50610557(CHEMBL5272625)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21940(Ghrelin | US20240190875, Example Ghrelin)
Affinity DataIC50: 0.25nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50: 0.255nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50610558(CHEMBL5269238)
Affinity DataIC50: 0.284nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM759861(US20250236608, Example 464)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759456((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759787((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50610556(CHEMBL5266033)
Affinity DataIC50: 0.334nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM759614(US20250236608, Example 206)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759662((1S,5S)—N-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759670(US20250236608, Example 264)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pontifical Catholic University of Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...)
Affinity DataKd: <0.400nMAssay Description:Binding affinity to Mycobacterium tuberculosis H37Rv InhA assessed as dissociation constant in presence of NADH, octenoyl-CoA and KatGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM759547(US20250236608, Example 136)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759620(US20250236608, Example 212)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759724(US20250236608, Example 318)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759788((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759842(US20250236608, Example 439)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759779((1S,5S)—N-(7-ethoxy-4-(3-(4-fluorophenyl)-1-methyl...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759847(US20250236608, Example 444)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759846(US20250236608, Example 443)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetGrowth hormone secretagogue receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267264(CHEMBL504776)
Affinity DataIC50: 0.420nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50610558(CHEMBL5269238)
Affinity DataIC50: 0.479nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM759703(US20250236608, Example 297)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759791((1S,5S)—N-(4-(1-ethyl-3-phenyl-1H-pyrazol-4-yl)-7-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759456((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759765(US20250236608, Example 362)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759700(US20250236608, Example 294)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759561(US20250236608, Example 153)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759544((S)-7-methoxy-4-(3-phenyl-1H-pyrazol-4-yl)-6-(tetr...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759424(US20250236608, Example 20)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759847(US20250236608, Example 444)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759670(US20250236608, Example 264)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759455((R)-4-(1-((7-methoxy-4-(1-methyl-3-phenyl-1H-pyraz...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759621(US20250236608, Example 213)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759890(US20250236608, Example 496)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759668((1R,5R)—N-(4-(1-ethyl-3-(2-fluorophenyl)-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759514((S)-1-(7-ethoxy-4-(1-methyl-3-phenyl-1H-pyrazol-4-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759849((R)-1-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759610(US20250236608, Example 202)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759528((S)-1-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazo...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759821(US20250236608, Example 418)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
Displayed 1 to 50 (of 1311 total ) | Next | Last >>
Jump to: