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TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338M](Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DatapH: 7.0 T: 2°CAssay Description:IC50 determinations for cSrc kinases were measured with the HTRF KinEASE-TK assay from Cisbio according to the manufacturer instructions. A biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338M](Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31826(CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...)
Affinity DatapH: 7.0 T: 2°CAssay Description:IC50 determinations for cSrc kinases were measured with the HTRF KinEASE-TK assay from Cisbio according to the manufacturer instructions. A biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338M](Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31830(quinazoline-pyrazolourea hybrid compound, 3d)
Affinity DatapH: 7.0 T: 2°CAssay Description:IC50 determinations for cSrc kinases were measured with the HTRF KinEASE-TK assay from Cisbio according to the manufacturer instructions. A biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50115216(CHEMBL87580 | 1-[2-(3-Amino-phenyl)-5-tert-butyl-2...)
Affinity DataAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataAssay Description:Tyrosine kinase inhibition assay using wild type cSrc measured by a fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31824(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataKd:  55nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50115216(CHEMBL87580 | 1-[2-(3-Amino-phenyl)-5-tert-butyl-2...)
Affinity DataKd:  197nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataKd:  12nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataKd:  8nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  495nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153702(2-(4-((4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...)
Affinity DataKd:  410nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153703(2-(4-((4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]im...)
Affinity DataKd:  150nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153704(2-(4-((3,4-Dihydroisoquinolin-2(1H)-yl)methyl)phen...)
Affinity DataKd:  6.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153705(Methyl 1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphth...)
Affinity DataKd:  900nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153706(2-(4-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)ph...)
Affinity DataKd:  7.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153707(3-Phenyl-2-(4-((4-(pyrimidin-2-yl)piperazin-1-yl)m...)
Affinity DataKd:  1.10E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153708(3-Phenyl-2-(4-((4-(tetrahydrofuran-2-carbonyl)pipe...)
Affinity DataKd:  8.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM50313650(8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...)
Affinity DataKd:  90nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153709(7-(4-methylphenyl)-5-phenyl-N-(thiophen-2-ylmethyl...)
Affinity DataKd:  2.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153710(7-(4-methylphenyl)-5-phenyl-N-(pyridin-3-ylmethyl)...)
Affinity DataKd:  7.80E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153711(7-(4-fluorophenyl)-5-phenyl-N-(pyridin-2-ylmethyl)...)
Affinity DataKd:  2.00E+4nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153712(5,7-diphenyl-N-(thiophen-2-ylmethyl)-7H-pyrrolo[2,...)
Affinity DataKd:  2.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153713(7-(3-methylphenyl)-5-phenyl-N-(thiophen-2-ylmethyl...)
Affinity DataKd:  9.90E+4nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153714(N-benzyl-7-(4-methylphenyl)-5-phenyl-7H-pyrrolo[2,...)
Affinity DataKd:  6.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit������T Dortmund

LigandPNGBDBM153715(7-(3-chloro-4-methylphenyl)-5-phenyl-N-(thiophen-2...)
Affinity DataKd:  2.64E+5nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464229(CHEMBL4290409)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464230(CHEMBL4291533)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464231(CHEMBL4283686)
Affinity DataEC50: >2.50E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464232(CHEMBL4284303)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464233(CHEMBL4293857)
Affinity DataEC50:  2.10E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataEC50:  700nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464235(CHEMBL4287359)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464236(CHEMBL4284350)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464237(CHEMBL4278843)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464238(CHEMBL4287695)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464239(CHEMBL4287774)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464240(CHEMBL4290216)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464241(CHEMBL4290185)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464242(CHEMBL4285933)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464243(CHEMBL4293822)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464244(CHEMBL4279071)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464245(CHEMBL4283192)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464246(CHEMBL4280193)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464247(CHEMBL4294144)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464248(CHEMBL4290217)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464249(CHEMBL4286392)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464250(CHEMBL4278475)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464251(CHEMBL4281948)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464252(CHEMBL4293193)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464253(CHEMBL4290872)
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
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