Report error Found 173 with Last Name = 'sintim' and Initial = 'ho'
Affinity DataKi: 330nMAssay Description:Inhibition of ROCK (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 20 mins in presence of [gamma33P]ATP by filter binding me...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 20 mins in presence of [gamma33P]ATP by filter binding me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal His-tagged human ROCK1 (3 to 543 residues) expressed in baculovirus infected Sf9 cells using biotin-Ahx-AKRRRLSSLRA-CONH2 as...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of N-terminal His-tagged human ROCK1 (3 to 543 residues) expressed in baculovirus infected Sf9 cells using biotin-Ahx-AKRRRLSSLRA-CONH2 as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human TrkC using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by H...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human GST-tagged ROCK2 (1 to 552 residues) using myelin basic protein as substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 (1 to 535 residues) using myelin basic protein as substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 20 mins in presence of [gamma33P]ATP by filter binding me...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 2 hrs by Hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
TargetRocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Competitive binding affinity to Pseudomonas aeruginosa PAO1 His6-tagged RocR expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of [32...More data for this Ligand-Target Pair
TargetRocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Maryland
Curated by ChEMBL
University of Maryland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Competitive binding affinity to Pseudomonas aeruginosa PAO1 His6-tagged RocR expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of [32...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 20 mins in presence of [gamma33P]ATP by filter binding me...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
