Report error Found 315 with Last Name = 'sridevi' and Initial = 'jp'
Affinity DataIC50: 46nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 180nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 930nMT: 37°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 990nMT: 37°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 1.01E+3nMT: 37°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 1.06E+3nMpH: 7.5 T: 37°CAssay Description:Reaction volumes of 0.4 mL of chorismate (typically, 1 mM) in 50 mM Tris-HCl (pH 7.5), 0.5 mM EDTA, 0.1 mg/mL bovine serum albumin, and 10 mM β-...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 1.08E+3nMT: 37°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 1.96E+3nMT: 37°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Curated by ChEMBL
Birla Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli BL21 (DE3) using 2-trans-decenoyl substrate by spectrophotome...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Curated by ChEMBL
Birla Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli BL21 (DE3) using 2-trans-decenoyl substrate by spectrophotome...More data for this Ligand-Target Pair
Affinity DataIC50: 3.14E+3nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT...More data for this Ligand-Target Pair
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...More data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.57E+3nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) pLysS cells after 100 mins by inorganic phosphate...More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT...More data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of 6-His-tagged Mycobacterium smegmatis GyrB expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 100 mins in presence of AT...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology
Birla Institute of Technology
Affinity DataIC50: 4.08E+3nMpH: 7.5 T: 37°CAssay Description:Reaction volumes of 0.4 mL of chorismate (typically, 1 mM) in 50 mM Tris-HCl (pH 7.5), 0.5 mM EDTA, 0.1 mg/mL bovine serum albumin, and 10 mM β-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.32E+3nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
