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TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  34nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  24nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  19nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  40nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092341(US9675697, Cpd. No. 22 | CHEMBL3581660)
Affinity DataKd:  28nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  26nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  20nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  29nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092310(US9675697, Cpd. No. 23 | CHEMBL3581661)
Affinity DataKd:  13nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  41nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  42nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  60nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  34nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  11nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  17nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  11nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  27nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179477(US9675697, Cpd. No. 44)
Affinity DataKd:  10nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217369(MEEVD)
Affinity DataKd:  140nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217370(IEEVD)
Affinity DataKd:  426nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217373(SSGPTIEEVD)
Affinity DataKd:  1.06E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217374(GSGPTIEEVD)
Affinity DataKd:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217371(DDTSRMEEVD)
Affinity DataKd:  79nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217372(EDASRMEEVD)
Affinity DataKd:  77nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217375(DVEEM)
Affinity DataKd: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217377(GSGPTMEEVD)
Affinity DataKd:  133nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217376(DDTSRIEEVD)
Affinity DataKd:  420nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human ATAD2A (Q981 to R1108 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human BRPF1 (E627 to G740 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human BRD2 bromodomain 1 (K71 to N194 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to human BRD2 bromodomain 2 (E348 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  0.800nMAssay Description:Binding affinity to human BRD4 bromodomain 2 (K333 to E460 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  110nMAssay Description:Binding affinity to human EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human TRIM24 (P790 to P977 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Inhibition of BRD8 bromodomain 1 (unknown origin) by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  0.520nMAssay Description:Binding affinity to human BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to human BRD4 bromodomain 1 (N44 to E168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to human BRDT bromodomain 2 (K250 to E382 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  47nMAssay Description:Binding affinity to human CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
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