Compile Data Set for Download or QSAR
Report error Found 128 with Last Name = 'tan' and Initial = 'st'
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataIC50: 4nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM476979(peptidomimetic coronavirus 3CLpro inhibitors 17)
Affinity DataIC50: 7nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataIC50: 8nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM476989(TG-0205221)
Affinity DataIC50: 9nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM420296(med.21724, Compound 61 | peptidomimetic aldehydes ...)
Affinity DataIC50: 14nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM420297(med.21724, Compound 62 | peptidomimetic aldehydes ...)
Affinity DataIC50: 23nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 30nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM420296(med.21724, Compound 61 | peptidomimetic aldehydes ...)
Affinity DataIC50: 31nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 31nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 34nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM420297(med.21724, Compound 62 | peptidomimetic aldehydes ...)
Affinity DataIC50: 40nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM476983(GC-373 | GC373)
Affinity DataIC50: 42nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM420296(med.21724, Compound 61 | peptidomimetic aldehydes ...)
Affinity DataIC50: 53nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM476979(peptidomimetic coronavirus 3CLpro inhibitors 17)
Affinity DataIC50: 65nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352142(CHEMBL1824770)
Affinity DataIC50: 69nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM476960(peptidomimetic coronavirus 3CLpro inhibitors 2i)
Affinity DataIC50: 94nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352145(CHEMBL1824773)
Affinity DataIC50: 134nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352143(CHEMBL1824771)
Affinity DataIC50: 155nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82106(6,8,10-Traiazaspiro[4.5]deca-6,8-diene-7,9-diamine...)
Affinity DataIC50: 173nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM11231(N-[(benzyloxy)carbonyl]-L-valyl-N1-((1S,2E)-4-etho...)
Affinity DataIC50: 286nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM476983(GC-373 | GC373)
Affinity DataIC50: 400nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352144(CHEMBL1824772)
Affinity DataIC50: 548nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226151(1-(4-Chloro-benzyl)-2,2-diisobutyl-2,3-dihydro-1H-...)
Affinity DataIC50: 600nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226149(1-Benzyl-2,2-diisobutyl-2,3-dihydro-1Hquinazolin-4...)
Affinity DataIC50: 800nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226138(1-(2-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-...)
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226143(1-(4-Chloro-benzyl)-2-(4-chloro-phenyl)-2-methyl-2...)
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226151(1-(4-Chloro-benzyl)-2,2-diisobutyl-2,3-dihydro-1H-...)
Affinity DataIC50: 1.56E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(SARS-CoV)
A*Star

LigandPNGBDBM476960(peptidomimetic coronavirus 3CLpro inhibitors 2i)
Affinity DataIC50: 1.70E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226145(1-Benzyl-2-isobutyl-2-methyl-2,3-dihydro-1H-quinaz...)
Affinity DataIC50: 1.70E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82113(1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226133(1-Benzyl-2,2-diethyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 1.80E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226123(1-(4-Chloro-benzyl)-2,2-dimethyl-2,3-dihydro-1H-qu...)
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226139(1-(4-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-...)
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226149(1-Benzyl-2,2-diisobutyl-2,3-dihydro-1Hquinazolin-4...)
Affinity DataIC50: 2.48E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM476985(MG-115)
Affinity DataIC50: 3.14E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226145(1-Benzyl-2-isobutyl-2-methyl-2,3-dihydro-1H-quinaz...)
Affinity DataIC50: 3.57E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226141(1-Benzyl-2-(4-chloro-phenyl)-2-methyl-2,3-dihydro-...)
Affinity DataIC50: 3.76E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226134(1-(2-Chloro-benzyl)-2,2-diethyl-2,3-dihydro-1Hquin...)
Affinity DataIC50: 3.80E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 3.90E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226135(1-(4-Chloro-benzyl)-2,2-diethyl-2,3-dihydro-1Hquin...)
Affinity DataIC50: 4.10E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataIC50: 4.13E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226143(1-(4-Chloro-benzyl)-2-(4-chloro-phenyl)-2-methyl-2...)
Affinity DataIC50: 4.48E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226133(1-Benzyl-2,2-diethyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 4.50E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226139(1-(4-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-...)
Affinity DataIC50: 4.60E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM50084655([(S)-1-((S)-1-Formyl-pentylcarbamoyl)-3-methyl-but...)
Affinity DataIC50: 4.81E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226137(1-Benzyl-2-methyl-2-propyl-2,3-dihydro-1H-quinazol...)
Affinity DataIC50: 5.30E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352146(CHEMBL1824776)
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataIC50: 5.40E+3nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 128 total ) | Next | Last >>
Jump to: