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TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21940(Ghrelin | US20240190875, Example Ghrelin)
Affinity DataEC50:  1.40nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21941(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1.90nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21942(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  3nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21943(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  5.5nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21944(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  14.6nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21945(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  3.80nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21946(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21947(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  10.1nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21948(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  82.5nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21949(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  3.30nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21950(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  7.90nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21951(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  9.5nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21952(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  45.3nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384288(Trans-2-(((2′-fluoro-5′-isopropoxy-[1,...)
Affinity DataEC50:  370nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384291((METHOD A) | US9938222, Example 2)
Affinity DataEC50:  250nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384292((METHOD A) | US9938222, Example 3)
Affinity DataEC50:  470nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384295(US9938222, Example 5 | Cis-2-(((2′-fluoro-5&...)
Affinity DataEC50:  470nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384295(US9938222, Example 5 | Cis-2-(((2′-fluoro-5&...)
Affinity DataEC50:  2.11E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384300((1R,2S)-Methyl 2-((4-bromophenoxy)methyl)cycloprop...)
Affinity DataEC50:  410nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384301(US9938222, Example 7 | (1R,2S)-2-(((2′-Fluor...)
Affinity DataEC50:  2.81E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384302((1S,2R)-2-(((2′-Fluoro-5′-isopropoxy-[...)
Affinity DataEC50:  2.86E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384305((Trans)-(+/−)-2-(((2′,3-difluoro-5R...)
Affinity DataEC50:  80nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384313((1R,2R)-2-(((2′,3-Difluoro-5′-phenoxy-...)
Affinity DataEC50:  80nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384305((Trans)-(+/−)-2-(((2′,3-difluoro-5R...)
Affinity DataEC50:  160nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384320(US9938222, Example 12 | US9938222, Example 14 | Tr...)
Affinity DataEC50:  310nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384322((1R,2R)-2-(((3′-Chloro-3-fluoro-5′-iso...)
Affinity DataEC50:  640nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384320(US9938222, Example 12 | US9938222, Example 14 | Tr...)
Affinity DataEC50:  830nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384301(US9938222, Example 7 | (1R,2S)-2-(((2′-Fluor...)
Affinity DataEC50:  1.69E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384338((1R,2S)-2-(2-(2′-Fluoro-5′-isopropoxy-...)
Affinity DataEC50:  420nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384340((1S,2R)-2-(2-(2′-Fluoro-5′-isopropoxy-...)
Affinity DataEC50:  200nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384345(Trans-2-(((2′-chloro-3-fluoro-5′-isopr...)
Affinity DataEC50:  210nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384348(Trans-2-((4-(6-fluoro-2,2-dimethyl-2,3-dihydrobenz...)
Affinity DataEC50:  990nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384353(2-((4-(5-Fluoro-2,2-dimethyl-2,3-dihydrobenzofuran...)
Affinity DataEC50:  1.25E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM384354(Trans-2-(((3′-fluoro-5′-phenoxy-[1,1&#...)
Affinity DataEC50:  660nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385605(Trans-2-(((2′-fluoro-5′-isopropoxy-[1,...)
Affinity DataEC50:  440nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385612(Trans-2-(((2′-fluoro-5′-phenoxy-[1,1&#...)
Affinity DataEC50:  980nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385613((1R,2R)-2-(4-(5-Chloro-2,2-dimethyl-2,3-dihydroben...)
Affinity DataEC50:  1.72E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385615(Trans-2-(4-(2-methyl-4-phenylthiazol-5-yl)phenethy...)
Affinity DataEC50:  1.23E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385620(Trans-2-(2-(2′-fluoro-5′-isopropoxy-[1...)
Affinity DataEC50:  320nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385692((1R,2R)-2-(2-(2′-fluoro-5′-isopropoxy-...)
Affinity DataEC50:  640nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385695((1S,2S)-2-(2-(2′-fluoro-5′-isopropoxy-...)
Affinity DataEC50:  990nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385715(US9938222, Example 33 | Trans-2-(2-((2′-fluo...)
Affinity DataEC50:  60nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385715(US9938222, Example 33 | Trans-2-(2-((2′-fluo...)
Affinity DataEC50:  430nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385744(Trans-(2-((2′-fluoro-5′-isopropoxy-[1,...)
Affinity DataEC50:  330nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385807(Trans-(2-((2′-fluoro-5′-isopropoxy-[1,...)
Affinity DataEC50:  60nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385822(Trans-2-((2′-fluoro-5′-isopropoxy-[1,1...)
Affinity DataEC50:  2.65E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385824(Trans-2-(2-(3′-(ethylthio)-[1,1′-biphe...)
Affinity DataEC50:  3.24E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385825(Cis-2-fluoro-2-(2-(2′-fluoro-5′-isopro...)
Affinity DataEC50:  2.02E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM385829(Trans-2-fluoro-2-(2-(2′-fluoro-5′-isop...)
Affinity DataEC50:  5.09E+3nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetFree fatty acid receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM386912(Trans-2-(2-(2′-fluoro-5′-isopropoxy-[1...)
Affinity DataEC50:  860nMAssay Description:For the pERK assay, 3×106 cells/mL cryopreserved human and mouse cells were thawed rapidly in a 37° C. water bath and added to a T-225 flask containi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

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