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TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600976(CHEMBL5200260)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600977(CHEMBL5178074)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600978(CHEMBL5184616)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600979(CHEMBL5188201)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50167161((E)-3-{3-[Cyclohexanecarbonyl-(4'-dimethylamino-bi...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600980(CHEMBL5173282)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600981(CHEMBL5192609)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600982(CHEMBL5174456)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600983(CHEMBL5192926)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600984(CHEMBL5206312)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600985(CHEMBL5187641)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600986(CHEMBL5175359)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600987(CHEMBL5184376)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600988(CHEMBL5170268)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600989(CHEMBL5203101)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600990(CHEMBL5199040)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600991(CHEMBL5189501)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600992(CHEMBL5184244)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600993(CHEMBL5169348)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600994(CHEMBL5174900)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600995(CHEMBL5208979)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600996(CHEMBL5208868)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600997(CHEMBL5176088)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAndrogen receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600998(CHEMBL1565119)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human AR expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEstrogen receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human ERalpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlucocorticoid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GR expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600999(CHEMBL5192460)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human LXR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterols receptor LXR-beta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600999(CHEMBL5192460)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human LXR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMineralocorticoid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM19214([3H]Aldosterone | (1S,2R,10S,11S,14S,15R,17S)-17-h...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human MR expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PPAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human PPAR-gamma expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human PPAR-delta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetProgesterone receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50410522(LEVONORGESTREL)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PR-alpha expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProgesterone receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50410522(LEVONORGESTREL)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRetinoic acid receptor alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human RAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRetinoic acid receptor beta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human RAR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human RXR-alpha expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human RXR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human THR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetThyroid hormone receptor beta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human THR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50601000(CHEMBL5206774)
Affinity DataEC50:  900nMAssay Description:Partial agonist activity at FXR (unknown origin) expressed in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunte...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50555362(CHEMBL4748172)
Affinity DataEC50:  2.64E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50632630(CHEMBL5427431)
Affinity DataEC50:  1.63E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50632633(CHEMBL5406591)
Affinity DataEC50:  2.91E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50632636(CHEMBL5431536)
Affinity DataEC50:  2.25E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50632641(CHEMBL5431290)
Affinity DataEC50:  6.52E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50632644(CHEMBL5397940)
Affinity DataEC50:  1.14E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  3.62E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM176555(US9120756, 17)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced TRPV1 activation by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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