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TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

LigandPNGBDBM81729(HSP90 Inhibitor, 1 | hsp90_125)
Affinity DataKd: <1.00E+4nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

LigandPNGBDBM50270588(HSP90 Inhibitor, 2 | CHEMBL504181 | 4-METHYL-6-(TR...)
Affinity DataKd:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

LigandPNGBDBM50270609(CHEMBL486921 | HSP90 Inhibitor, 3 | (3E)-3-[(pheny...)
Affinity DataKd:  1.50E+5nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Mouse)
Abbvie

US Patent
LigandPNGBDBM178731(US9125913, 300)
Affinity DataAssay Description:The inhibition constant (Ki) is the dissociation constant of an enzyme-inhibitor complex or a protein/small molecule complex, wherein the small molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209055(US9266877, 1)
Affinity DataEC50:  425nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209057(US9266877, 3)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209059(US9266877, 5)
Affinity DataEC50:  408nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209063(US9266877, 9)
Affinity DataEC50:  378nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209065(US9266877, 11)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209066(US9266877, 12)
Affinity DataEC50:  51nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209067(US9266877, 13)
Affinity DataEC50:  498nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209068(US9266877, 14)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209069(US9266877, 15)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209071(US9266877, 17)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209072(US9266877, 18)
Affinity DataEC50:  621nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209073(US9266877, 19)
Affinity DataEC50:  398nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209074(US9266877, 20)
Affinity DataEC50:  13nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209075(US9266877, 21)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209076(US9266877, 22)
Affinity DataEC50:  214nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209077(US9266877, 23)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209078(US9266877, 24)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209079(US9266877, 25)
Affinity DataEC50:  377nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209080(US9266877, 26)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209081(US9266877, 27)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209082(US9266877, 28)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209083(US9266877, 29)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209084(US9266877, 30)
Affinity DataEC50:  298nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209085(US9266877, 31)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209086(US9266877, 32)
Affinity DataEC50:  216nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209087(US9266877, 33)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209088(US9266877, 34)
Affinity DataEC50:  907nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209090(US9266877, 36)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209091(US9266877, 37)
Affinity DataEC50:  347nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209092(US9266877, 38)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209093(US9266877, 39)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209094(US9266877, 40)
Affinity DataEC50:  570nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209095(US9266877, 41)
Affinity DataEC50:  11nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209096(US9266877, 42)
Affinity DataEC50:  233nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209097(US9266877, 43)
Affinity DataEC50:  4nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209098(US9266877, 44)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209099(US9266877, 45)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209100(US9266877, 46)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209101(US9266877, 47)
Affinity DataEC50:  881nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209102(US9266877, 48)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209103(US9266877, 49)
Affinity DataEC50:  12nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209104(US9266877, 50)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209105(US9266877, 51)
Affinity DataEC50: >1.00E+3nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209106(US9266877, 52)
Affinity DataEC50:  570nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209107(US9266877, 53)
Affinity DataEC50:  387nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
Abbvie

US Patent
LigandPNGBDBM209108(US9266877, 54)
Affinity DataEC50:  501nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent

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