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TargetHeat shock-related 70 kDa protein 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to HspA2 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeat shock 70 kDa protein 6(Homo sapiens)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to HspA6 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd:  334nMAssay Description:Binding affinity to HspA5 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetStress-70 protein, mitochondrial(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd:  7.48E+3nMAssay Description:Binding affinity to HspA9 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeat shock cognate 71 kDa protein(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to HspA8 (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to HspA1A (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHeat shock 70 kDa protein 1-like(Homo sapiens)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50617289(CHEMBL5431926)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to HspA1L (unknown origin) assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50032737(CHEMBL3354718)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061594(CHEMBL3394041)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061587(CHEMBL3394051)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061585(CHEMBL3394049)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061584(CHEMBL3394048)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061582(CHEMBL3394039)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061580(CHEMBL3394057)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061593(CHEMBL3394040)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061599(CHEMBL3394046)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061588(CHEMBL3394052)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061598(CHEMBL3394045)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50226811(CHEMBL3349972)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061592(CHEMBL3394056)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061591(CHEMBL3394055)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061590(CHEMBL3394054)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061581(CHEMBL3394058)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50405541(CHEMBL2079670)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061586(CHEMBL3394050)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367258(CI-928 | QUINAPRILAT)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021530(CHEMBL58042 | (S,S,S) 2-[2-(1-Carboxy-3-phenyl-pro...)
Affinity DataIC50: 3nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021532(CHEMBL58480 | (S,S,S) 2-[2-(1-Carboxy-3-phenyl-pro...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50027141(1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50421824(CHEMBL75752)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061589(CHEMBL3394053)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061583(CHEMBL3394047)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061585(CHEMBL3394049)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50032737(CHEMBL3354718)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061582(CHEMBL3394039)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061587(CHEMBL3394051)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021795((R,R+S,S) 1-(3-Mercapto-2-methyl-propionyl)-octahy...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021525(CHEMBL61811 | (S,S,S) 2-[2-(1-Carboxy-3-phenyl-pro...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021808(CHEMBL368598 | Decahydro-8-thia-4b-aza-benzo[a]azu...)
Affinity DataIC50: 7nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061595(CHEMBL3394042)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061593(CHEMBL3394040)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061594(CHEMBL3394041)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50368166(Accupril | QUINAPRIL)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of guinea pig angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061584(CHEMBL3394048)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021807(CHEMBL110375 | (S,S)1-(3-Mercapto-2-methyl-propion...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061586(CHEMBL3394050)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021784((SSS)1-[2-(1-Carboxy-3-phenyl-propylamino)-propion...)
Affinity DataIC50: 11nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50061596(CHEMBL3394043)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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