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TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691452(US20240279201, Compound YA6139)
Affinity DataIC50: 0.110nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691451(US20240279201, Compound YA6138)
Affinity DataIC50: 0.150nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691520(US20240279201, Compound YA4155)
Affinity DataIC50: 0.400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691539(US20240279201, Compound YA4025)
Affinity DataIC50: 0.400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691495(US20240279201, Compound YA4029)
Affinity DataIC50: 0.460nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691495(US20240279201, Compound YA4029)
Affinity DataIC50: 0.460nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691521(US20240279201, Compound YA4165)
Affinity DataIC50: 0.5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50260529(CHEMBL4077626)
Affinity DataKd:  0.570nMAssay Description:Binding affinity to human BCL6 BTP domain assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691516(US20240279201, Compound YA4001)
Affinity DataIC50: 0.760nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691498(US20240279201, Compound YA6027)
Affinity DataIC50: 0.800nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691541(US20240279201, Compound YA4019)
Affinity DataIC50: 0.900nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50260529(CHEMBL4077626)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BCL6 BTP domain by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691538(US20240279201, Compound YA4007)
Affinity DataIC50: 1.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50592568(CHEMBL5174802)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691532(US20240279201, Compound YA6179)
Affinity DataIC50: 1.40nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50592567(CHEMBL5200990)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691450(US20240279201, Compound YA6141)
Affinity DataIC50: 1.70nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691500(US20240279201, Compound YA4003)
Affinity DataIC50: 1.80nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691454(US20240279201, Compound YA6136)
Affinity DataIC50: 1.80nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691447(US20240279201, Compound YA6045)
Affinity DataIC50: 1.80nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50592565(CHEMBL4555217 | US20240279201, Compound YW2065)
Affinity DataIC50: 2.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50592565(CHEMBL4555217 | US20240279201, Compound YW2065)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691508(US20240279201, Compound YA6090)
Affinity DataIC50: 2.5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50239363(CHEMBL4094351)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human BCL6 BTP domain measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691519(US20240279201, Compound YA6168)
Affinity DataIC50: 3.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691510(US20240279201, Compound YA1042)
Affinity DataIC50: 3.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691534(US20240279201, Compound YA6143)
Affinity DataIC50: 3.60nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691477(US20240279201, Compound YA4103)
Affinity DataIC50: 4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691428(US20240279201, Compound YA10951 | US20240279201, C...)
Affinity DataIC50: 4.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691428(US20240279201, Compound YA10951 | US20240279201, C...)
Affinity DataIC50: 4.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691507(US20240279201, Compound YA1084)
Affinity DataIC50: 4.70nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandPNGBDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to human mPGES-2 (1 to 87 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330882(CHEMBL1277951 | CHEMBL594682 | N1-((3R,4R)-4-((6-a...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691527(US20240279201, Compound YA4033)
Affinity DataIC50: 5.80nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691453(US20240279201, Compound YA6137)
Affinity DataIC50: 6nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50239363(CHEMBL4094351)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to human BCL6 BTP domain assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691536(US20240279201, Compound YA4009)
Affinity DataIC50: 6.70nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328814(6-{{(3''R,4''R)-3''-[2''''-(3''''''-Fluorophenethy...)
Affinity DataKi:  7nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328814(6-{{(3''R,4''R)-3''-[2''''-(3''''''-Fluorophenethy...)
Affinity DataKi:  7nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691522(US20240279201, Compound YA6172)
Affinity DataIC50: 7.60nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691494(US20240279201, Compound YA6029)
Affinity DataIC50: 7.82nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691533(US20240279201, Compound YA4011)
Affinity DataIC50: 8.20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM691542(US20240279201, Compound YA4017)
Affinity DataIC50: 8.20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

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